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probe activation kinetics

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2 results in Keywords: probe activation kinetics

Biological and Medicinal Chemistry

Piperazine-fused cyclic disulfides: high-performance bioreduction-activated cores for bifunctional probes and reagents

Lukas Zeisel, Jan G. Felber, Karoline C. Scholzen, Carina Schmitt, Alexander J. Wiegand, Leonid Komissarov, Elias S. J. Arnér, Oliver Thorn-Seshold

Version 2 posted 10 October 2023

1,268

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Biological and Medicinal Chemistry

Bicyclic selenenyl sulfides tune stepwise rates of thiol/selenol addition, resolution, and cyclisation, to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase

Lukas Zeisel, Lucas Dessen-Weissenhorn, Karoline C. Scholzen, Andrea Madabeni, Laura Orian, Elias S. J. Arnér, Oliver Thorn-Seshold

Version 1 posted 25 February 2025

190

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