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5 results in Keywords: pharmacology

Biological and Medicinal Chemistry

Non-covalent spin labelling of TRPC5 ion channels enables EPR studies of protein-ligand interactions

Aidan V. Johnson, Sebastian Alin Porav, Kasia L. R. Hammond, Anokhi Shah, Joshua L. Wort, Yue Ma, Hassane El Mkami, Christopher M. Pask, Stephen P. Muench, Andrew J. Wilson, Christos Pliotas, Robin S. Bon

Version 1 posted 19 September 2024

236

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Theoretical and Computational Chemistry

Actionable predictions of human pharmacokinetics at the drug design stage

Leonid Komissarov, Nenad Manevski, Katrin Groebke Zbinden, Torsten Schindler, Marinka Zitnik, Lisa Sach-Peltason

Version 1 posted 06 March 2024

539

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Biological and Medicinal Chemistry

An open-access tool for designing drug control into engineered proteins

Sam M Ireland, Christopher Southan, Alazane Dominguez-Monedero, Simon D. Harding, Joanna L. Sharman, Jamie A. Davies

Version 1 posted 06 April 2018

934

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Biological and Medicinal Chemistry

Challenges of Connecting Chemistry to Pharmacology: Perspectives from Curating the IUPHAR/BPS Guide to PHARMACOLOGY

Christopher Southan, Joanna L Sharman, Elena Faccenda, Adam J Pawson, Simon D Harding, Jamie A Davies

Version 1 posted 03 May 2018

923

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Biological and Medicinal Chemistry

Cell-Specific Chemical Delivery Using a Selective Nitroreductase–Nitroaryl Pair

Todd D. Gruber, Chithra Krishnamurthy, Jonathan B. Grimm, Michael R. Tadross, Laura M. Wysocki, Zev J. Gartner, Luke D. Lavis

Version 1 posted 06 June 2018

708

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