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Biological and Medicinal Chemistry

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organocatalytic switches

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2 results in Keywords: organocatalytic switches

Biological and Medicinal Chemistry

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches of DNA Repair Enzyme OGG1

Marek Varga, Florian Ortis, Emily Hank, Kaixin Zhou, Emma Scaletti Hutchinson, Alicia del Prado, Elisée Wiita, Alice Eddershaw, Natalie Rudolfova, Ingrid Almlöf, Stella Karsten, Kirill Mamonov, Kirsty Bentley, Olov Wallner, Evert J Homan, Martin Scobie, Thomas Helleday, Pål Stenmark, Miguel de Vega, Allan J. B. Watson, Maurice Michel

Version 1 posted 02 June 2025

94

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Biological and Medicinal Chemistry

Organocatalytic switches of OGG1 control ultrafast abasic site incision through compound pKa

Mario Kehler, Kaixin Zhou, Aurino Kemas, Alicia del Prado, Emma Scaletti Hutchinson, Elinor Hesslefors Nairn, Marek Varga, Yvonne Plattner, Yi Zong, Oryn Purewal-Sidhu, James Haslam, Elisee Wiita, Heather Gildie, Karolina Singerova, Zuzanna Szaruga, Ingrid Almlöf, Femke Hormann, Kang-Cheng Liu, Olov Wallner, Florian Ortis, Evert Homan, Opher Gileadi, Sean Rudd, Pål Stenmark, Miguel de Vega, Thomas Helleday, Nicholas D'Arcy-Evans, Volker Lauschke, Maurice Michel

Version 1 posted 13 March 2025

158

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