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Organic Chemistry

Working Paper

Diarylation of N- and O-nucleophiles through a metal-free cascade reaction

Erika Linde, David Bulfield, Gabriella Kervefors, Nibadita Purkait, Berit Olofsson

Version 1 posted 16 July 2021

705

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Biological and Medicinal Chemistry

Working Paper

Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)

Stefan Gerstenecker, Lisa Haarer, Martin Schröder, Mark Kudolo, Martin P. Schwalm, Valentin Wydra, Ricardo Serafim, Apirat Chaikuad, Stefan Knapp, Stefan Laufer, Matthias Gehringer

Version 1 posted 15 July 2021

322

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Organic Chemistry

Working Paper

Synthesis of Bench-Stable N-Quaternized Ketene N,O-Acetals and Preliminary Evaluation as Reagents in Organic Synthesis

Danielle L. McConnell, Alisha M. Blades, Danielle Gomes Rodrigues, Phoebe V. Keyes, Justin C. Sonberg, Caitlin E. Anthony, Sofia Rachad, Olivia M. Simone, Caroline F. Sullivan, Jonathan D. Shapiro, Christopher C. Williams, Benjamin C. Schafer, Amy Glanzer, Holly Hutchinson, Ashley Thayaparan, Zoe Krevlin, Isabella Bote, Yasin Haffary, Sambat Bhandari, Jack A. Goodman, Max Majireck

Version 2 posted 26 July 2021

1,079

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Organic Chemistry

Working Paper

Machine Learning Meets Mechanistic Modelling for Accurate Prediction of Experimental Activation Energies

Kjell Jorner, Tore Brinck, Per-Ola Norrby, David Buttar

Version 1 posted 05 August 2020

1,041

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Organic Chemistry

Working Paper

Synthesis of Highly Functionalized Diarylamines through an N-, C-Cascade Reaction via Ammonium Salts

Erika Linde, Berit Olofsson

Version 1 posted 18 April 2023

419

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Inorganic Chemistry

Working Paper

Improved Synthesis of Icosahedral Carboranes Containing Exohedral B–c and C–c Bonds

Kierstyn P. Anderson, Harrison A. Mills, Chantel Mao, Kent O. Kirlikovali, Jonathan C. Axtell, Arnold L. Rheingold, Alexander Spokoyny

Version 1 posted 26 October 2018

622

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Organic Chemistry

Working Paper

A revised synthesis of 6-alkoxy-2-aminopurines with late-stage convergence allowing for increased molecular complexity

Lavleen Mader, John Hayward, Lisa Porter, John Trant

Version 1 posted 06 May 2022

254

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Organic Chemistry

Working Paper

A generally applicable quantitative reactivity model for nucleophilic aromatic substitution built from simple descriptors

Jingru Lu, Irina Paci, David Leitch

Version 1 posted 19 July 2022

771

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Biological and Medicinal Chemistry

Working Paper

Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles

Moritz Schwarz, Maksym Kurkunov, Florian Wittlinger, Ramona Rudalska, Guiqun Wang, Martin P. Schwalm, Alexander Rasch, Benedikt Wagner, Stefan A. Laufer, Stefan Knapp, Daniel Dauch, Matthias Gehringer

Version 2 posted 25 March 2024

821

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Organic Chemistry

Working Paper

Bicyclic-ammonium-incorporated ylidic nitrogen groups for strong π-electron donation in push–pull benzene π-conjugated systems

Hikaru Fujita, Takanari Arai, Naoto Kuchiki, Munetaka Kunishima

Version 1 posted 21 March 2024

151

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Refine Search

11 results in nucleophilic aromatic substitution in Keywords: nucleophilic aromatic substitution

Diarylation of N- and O-nucleophiles through a metal-free cascade reaction

Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)

Synthesis of Bench-Stable N-Quaternized Ketene N,O-Acetals and Preliminary Evaluation as Reagents in Organic Synthesis

Machine Learning Meets Mechanistic Modelling for Accurate Prediction of Experimental Activation Energies

Synthesis of Highly Functionalized Diarylamines through an N-, C-Cascade Reaction via Ammonium Salts

Improved Synthesis of Icosahedral Carboranes Containing Exohedral B–c and C–c Bonds

A revised synthesis of 6-alkoxy-2-aminopurines with late-stage convergence allowing for increased molecular complexity

A generally applicable quantitative reactivity model for nucleophilic aromatic substitution built from simple descriptors

Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles

Bicyclic-ammonium-incorporated ylidic nitrogen groups for strong π-electron donation in push–pull benzene π-conjugated systems

11 results in Keywords: nucleophilic aromatic substitution