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nirmatrelvir

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3 results in Keywords: nirmatrelvir

Organic Chemistry

A Sustainable Synthesis of the SARS-CoV-2 Mpro Inhibitor Nirmatrelvir, the Active Ingredient in Paxlovid

Joseph R. A. Kincaid, Juan C. Caravez, Karthik S. Iyer, Rahul D. Kavthe, Nico Fleck, Donald H. Aue, Bruce H. Lipshutz

Version 2 posted 14 July 2022

1,712

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1

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Organic Chemistry

Efforts to Develop a Cost-Effective and Scalable Synthetic Process for Nirmatrelvir

Charles S. Shanahan, Appasaheb L. Kadam, Barreddi Chiranjeevi, Aline A. Nunes, Aravindan Jayaraman, Saeed Ahmad, Sarah L. Aleshire, Kai O. Donsbach, B. Frank Gupton, Michel C. Nuckols

Version 1 posted 08 August 2022

1,050

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6

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Theoretical and Computational Chemistry

A Computational Comparison Between Pomotrelvir and Nirmatrelvir Binding and Reactivity with SARS-CoV-2 Main Protease. Implications for Resistance Mechanisms

Johanna Schillings, Carlos A. Ramos-Guzmán, J. Javier Ruiz-Pernía, Iñaki Tuñón

Version 1 posted 17 January 2024

211

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