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4-anilinoquinazoline derivatives as the first potent NOD1-RIPK2 signaling pathway inhibitors at the nanomolar range with potential anti-inflammatory activity

Amélie BARCZYK, Perrine SIX, Morgane RIVOAL, Claire DEVOS, Xavier DEZITTER, Min-Jeong CORNU-CHOI, Karine HUARD, Erika PELLEGRINI, Stephen CUSACK, Laurent DUBUQUOY, Régis MILLET, Natascha LELEU-CHAVAIN

Version 1 posted 26 April 2024

140

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1

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Nanoscience

Working Paper

Gold nanoclusters/MIL-100(Fe) bimodal nanovector for the therapy of inflammatory disease through attenuation of Toll-like receptor signaling.

Heng Zhao, Sonia Becharef, Eddy Dumas, Florent Carn, Gilles Patriarche, Simona Mura, Florence Gazeau, Christian Serre, NATHALIE STEUNOU

Version 1 posted 01 November 2023

194

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Biological and Medicinal Chemistry

Working Paper

Light-controlled inhibition of the circadian regulator RORγ

Martin Reynders, Sabine Willems, Julian A. Marschner, Thomas Wein, Daniel Merk, Oliver Thorn-Seshold

Version 1 posted 31 July 2023

304

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Materials Science

Working Paper

Activatable Superparamagnetic Iron Oxide Nanoparticles Scavenge Reactive Oxygen Species in Macrophages and Endothelial Cells

Chukwuazam Nwasike, Eunsoo Yoo, Erin Purr, Amber L. Doiron

Version 1 posted 28 August 2020

385

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Biological and Medicinal Chemistry

Working Paper

Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19

Corleone Delaveris, Aaron Wilk, Nicholas Riley, Jessica Stark, Samuel Yang, Angela Rogers, Thanmayi Ranganath, Kari Nadeau, Catherine Blish, Carolyn Bertozzi

Version 1 posted 17 December 2020

1,201

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Biological and Medicinal Chemistry

Working Paper

Diarylidene-N-Methyl-4-Piperidone and Spirobibenzopyran Curcumin Analogues as Antioxidant and Anti-Inflammatory Pharmacophores

R. Siva Kumar, Javier Mas-Rosario, Bishnu Joshi, Mayank Joshi, Angshuman Roy Choudhury, Swayamsiddha Kar, G. Nageswara Rao, Michelle Farkas

Version 1 posted 27 January 2023

184

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Biological and Medicinal Chemistry

Review

Polyphenolic Promiscuity, Inflammation-coupled Specificity: Whether PAINs Filters Mask an Antiviral Asset

Rick Sheridan, Kevin Spelman

Version 1 posted 23 March 2022

234

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Biological and Medicinal Chemistry

Working Paper

Groebke Blackburn Bienaymé-mediated multi-component synthesis of selective HDAC6 inhibitors with anti-inflammatory properties

Fabian Kraft, Jana Enns, Irina Honin, Jonas Engelhardt, Andrea Schöler, Shannon Smith, Jens Meiler, Linda Schäker-Hübner, Günther Weindl, Finn Kristian Hansen

Version 2 posted 19 December 2023

229

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Earth, Space, and Environmental Chemistry

Working Paper

Differential cardiovascular effects of nano- and micro-particles in mice: Implications for ultrafine and fine particle disease burden in humans

Marin Kuntic, Ivana Kuntic, Dirk Cleppien, Andrea Pozzer, David Nußbaum, Matthias Oelze, Tristan Junglas, Lea Strohm, Henning Ubbens, Steffen Daub, Maria Teresa Bayo Jimenez, Sven Danckwardt, Thomas Berkemeier, Omar Hahad, Matthias Kohl, Sebastian Steven, Albrecht Stroh, Jos Lelieveld, Thomas Münzel, Andreas Daiber

Version 1 posted 10 October 2024

82

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Biological and Medicinal Chemistry

Working Paper

Efficacy and toxicity analysis of selective BET bromodomain inhibitors in models of inflammatory liver disease

Luke Doskey, Cole Scholtz, Nora Vail, Shalil Khanal, Amani Lee, Sai Giridhar Sarma Kandanur, Zachariah Hoell, Amelia Huehls, Mohamed Issa, Enis Kostallari, Sheng Cao, Joel Reid, Harmeet Malhi, Vijay Shah, william pomerantz

Version 1 posted 24 October 2024

95

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10 results in inflammation in Keywords: inflammation

4-anilinoquinazoline derivatives as the first potent NOD1-RIPK2 signaling pathway inhibitors at the nanomolar range with potential anti-inflammatory activity

Gold nanoclusters/MIL-100(Fe) bimodal nanovector for the therapy of inflammatory disease through attenuation of Toll-like receptor signaling.

Light-controlled inhibition of the circadian regulator RORγ

Activatable Superparamagnetic Iron Oxide Nanoparticles Scavenge Reactive Oxygen Species in Macrophages and Endothelial Cells

Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19

Diarylidene-N-Methyl-4-Piperidone and Spirobibenzopyran Curcumin Analogues as Antioxidant and Anti-Inflammatory Pharmacophores

Polyphenolic Promiscuity, Inflammation-coupled Specificity: Whether PAINs Filters Mask an Antiviral Asset

Groebke Blackburn Bienaymé-mediated multi-component synthesis of selective HDAC6 inhibitors with anti-inflammatory properties

Differential cardiovascular effects of nano- and micro-particles in mice: Implications for ultrafine and fine particle disease burden in humans

Efficacy and toxicity analysis of selective BET bromodomain inhibitors in models of inflammatory liver disease

10 results in Keywords: inflammation