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Mechanism of Action of KL-50, a Novel Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

Eric Huseman, Anna Lo, Olga Fedorova, James Elia, Susan Gueble, Kingson Lin, Ranjini Sundaram, Danielle Burgenske, Joonseok Oh, Jinchan Liu, Fabian Menges, Matthew Rees, Melissa Ronan, Jennifer Roth, Victor Batista, Jason Crawford, Jann Sarkaria, Anna Pyle, Ranjit Bindra, Seth Herzon

Version 1 posted 13 June 2023

613

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Nanoscience

Working Paper

Periodic table screening for enhanced positive contrast in MRI and in vivo uptake in glioblastoma

Aitor Herraiz, M. Puerto Morales, Lydia Martínez-Parra, Nuria Arias-Ramos, Pilar López-Larrubia, Lucía Gutierrez, Jesús Mejías, Carlos Díaz-Ufano, Jesús Ruiz-Cabello, Fernando Herranz

Version 2 posted 19 January 2024

283

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Physical Chemistry

Working Paper

Fluorescence lifetime imaging unravels the pathway of glioma cell death upon hypericin-induced photodynamic therapy

Miriam Bassler, Jonas Hiller, Frank Wackenhut, Sven zur Oven-Krockhaus, Philipp Frech, Felix Schmidt, Christoph Kertzscher, Tim Rammler, Rainer Ritz, Kai Braun, Marcus Scheele, Alfred J. Meixner, Marc Brecht

Version 1 posted 21 November 2023

264

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles

Dorota Lubanska, Sami Alrashed, Gage T. Mason, Fatima Nadeem, Mitchell DiPasquale, Angela Awada, Aleena Malik, Mohamed A. R. Soliman, Ana C. deCarvalho, Abdalla Shamisa, Swati Kulkarni, Drew Marquardt, Lisa A. Porter, Simon Rondeau-Gagné

Version 2 posted 16 September 2021

382

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Biological and Medicinal Chemistry

Working Paper

Epitranscriptome-wide Approach for Identifying Specific Writer of RNA Modification as Knockdown Target for Resensitizing Glioblastoma Cells to Temozolomide Treatment

Norman Chiu, Jennifer Simpson, Frank Morales Shnaider, Renata Fleming, Bakhos Tannous

Version 1 posted 29 August 2024

83

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Biological and Medicinal Chemistry

Working Paper

Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

José Marco-Contelles, Daniel Diez-Iriepa, Mireia Toledano-Pinedo, Alicia Porro, Pedro Almendros, M. Mercedes Rodríguez-Fernández,, Abdelouahid Samadi, Isabel Iriepa, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu

Version 1 posted 12 May 2023

250

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Biological and Medicinal Chemistry

Working Paper

Synthesis and Biological Evaluation of tert-Butyl Ester and Ethyl Ester Prodrugs of L-γ-Methyleneglutamic Acid Amides for Cancer

Md Imdadul Khan, Fakhri Mahdi, Patrice Penfornis, Nicholas Akins, Md Imran Hossain, Seong Jong Kim, Suresh Sulochana, Amna Adam, Tristan Tran, Chalet Tan, Pier Paolo Claudio, Jason Paris, Hoang Le

Version 2 posted 27 October 2022

524

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Biological and Medicinal Chemistry

Working Paper

A novel blood brain barrier-permeable IRE1 kinase inhibitor for adjuvant glioblastoma treatment in mice.

Diana Pelizzari-Raymundo, Dimitrios Doultsinos, Raphael Pineau, Chloé Sauzay, Thodoris Koutsandreas, Antonio Carlesso, Elena Gkotsi, Luc Negroni, Tony Avril, Aristotelis Chatziioannou, Eric Chevet, Leif A. Eriksson, Xavier Guillory

Version 3 posted 18 January 2023

1,144

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8 results in glioblastoma in Keywords: glioblastoma

Mechanism of Action of KL-50, a Novel Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

Periodic table screening for enhanced positive contrast in MRI and in vivo uptake in glioblastoma

Fluorescence lifetime imaging unravels the pathway of glioma cell death upon hypericin-induced photodynamic therapy

Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles

Epitranscriptome-wide Approach for Identifying Specific Writer of RNA Modification as Knockdown Target for Resensitizing Glioblastoma Cells to Temozolomide Treatment

Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

Synthesis and Biological Evaluation of tert-Butyl Ester and Ethyl Ester Prodrugs of L-γ-Methyleneglutamic Acid Amides for Cancer

A novel blood brain barrier-permeable IRE1 kinase inhibitor for adjuvant glioblastoma treatment in mice.

8 results in Keywords: glioblastoma