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Organic Chemistry

Working Paper

The Ugi-Smiles Reaction on Steroids: Discovery of Bioactive N,N-Disubstituted 3- Aminoestrones

Cecilia Attorresi, Bruno Falcone, Evelyn Bonifazi, Gabriel Gola, Andrea Barquero, Javier Alberto Ramirez

Version 1 posted 07 September 2020

480

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Organic Chemistry

Working Paper

Chemoenzymatic Multicomponent Synthesis of Nirmatrelvir

Hans Daniel Preschel, Ruben T. Otte, Ying Zhuo, Rebecca E. Ruscoe, Ashleigh J. Burke, Rachel Cowan, Brendan Horst, Sven Hennig, Elwin Janssen, Anthony Green, Nicholas J. Turner, Eelco Ruijter

Version 1 posted 27 June 2022

1,145

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2

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Biological and Medicinal Chemistry

Working Paper

Unlocking the Antiviral Arsenal: Multiparametric Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E

Christina Karhan, Svenja Mareike Sake, Antonia Patricia Gunesch, Christina Grethe, Benedikt Hellwinkel, Alexander Felix Kiefer, Uladzislau Hapko, Andreas Martin Kany, Thomas Pietschmann, Anna Katharina Herta Hirsch

Version 1 posted 13 February 2024

207

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Biological and Medicinal Chemistry

Working Paper

Strategic Fluorination to Achieve a Potent, Selective, Metabolically-Stable, and Orally-Bioavailable Inhibitor of CSNK2.

Han Wee Ong, Xuan Yang, Jeffery Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah Dickmander, Tammy Havener, Marcia Sanders, Jason Brown, Rafael Couñago, Edcon Chang, Andreas Krämer, Nathaniel Moorman, Mark Heise, Alison Axtman, David Drewry, Timothy Willson

Version 1 posted 22 July 2024

80

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Materials Science

Working Paper

Functional Ionic Porous Frameworks Based on Triaminoguanidinium for CO2 Conversion and Combating Microbes

MD. Waseem Hussain, Vipin Bhardwaj, ARKAPRABHA GIRI, Ajit Chande, Abhijit Patra

Version 1 posted 27 November 2019

603

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Biological and Medicinal Chemistry

Working Paper

Simultaneous Inhibition of Entry and Replication of Novel Corona Virus by Grazoprevir: A Computational Drug Repurposing Study

Santosh Kumar Behera, Nazmina Vhora, Darshan Contractor, Amit Shard, Dinesh Kumar, Kiran Kalia, Alok Jain

Version 1 posted 05 June 2020

718

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Biological and Medicinal Chemistry

Working Paper

New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides

Luca Sancineto, Francesca Mangiavacchi, Agnieszka Dąbrowska, Agata Pacuła, Magdalena Obieziurska-Fabisiak, Veronica Ceccucci, Cecilia Scimmi, Juan Kong, Yao Zhao, Gianluca Ciancaleoni, Vanessa Nascimento, Bruno Rizzuti, Anna Kula-Pacurar, Haitao Yang, Jacek Ścianowski, Ying Lei, Krzysztof Pyrc, Claudio Santi

Version 2 posted 12 March 2024

1,048

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Theoretical and Computational Chemistry

Working Paper

Compilation of Potential Protein Targets for SARS-CoV-2: Preparation of Homology Model and Active Site Determination for Future Rational Antiviral Design

Sourav Pal, Dr. Arindam Talukdar

Version 1 posted 06 April 2020

1,377

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Biological and Medicinal Chemistry

Working Paper

Repurposing of FDA Approved Drugs for the Identification of Potential Inhibitors of SARS-CoV-2 Main Protease

Abhik Kumar Ray, Parth Sarthi Sen Gupta, Saroj Kumar Panda, Satyaranjan Biswal, Malay Kumar Rana

Version 2 posted 14 May 2020

1,223

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2

Citations

Biological and Medicinal Chemistry

Working Paper

Structure-Based Virtual Screening and Molecular Dynamics of Phytochemicals Derived from Saudi Medicinal Plants to Identify Potential COVID-19 Therapeutics

MUBARAK ALAMRI, Ali Altharawi, Alhumaidi B. Alabbas, Manal A. Alossaimi, Safar M. Alqahtani

Version 1 posted 21 May 2020

1,390

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Refine Search

32 results in antiviral in Keywords: antiviral

The Ugi-Smiles Reaction on Steroids: Discovery of Bioactive N,N-Disubstituted 3- Aminoestrones

Chemoenzymatic Multicomponent Synthesis of Nirmatrelvir

Unlocking the Antiviral Arsenal: Multiparametric Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E

Strategic Fluorination to Achieve a Potent, Selective, Metabolically-Stable, and Orally-Bioavailable Inhibitor of CSNK2.

Functional Ionic Porous Frameworks Based on Triaminoguanidinium for CO2 Conversion and Combating Microbes

Simultaneous Inhibition of Entry and Replication of Novel Corona Virus by Grazoprevir: A Computational Drug Repurposing Study

New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides

Compilation of Potential Protein Targets for SARS-CoV-2: Preparation of Homology Model and Active Site Determination for Future Rational Antiviral Design

Repurposing of FDA Approved Drugs for the Identification of Potential Inhibitors of SARS-CoV-2 Main Protease

Structure-Based Virtual Screening and Molecular Dynamics of Phytochemicals Derived from Saudi Medicinal Plants to Identify Potential COVID-19 Therapeutics

32 results in Keywords: antiviral