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Exploring and expanding the natural chemical space of bacterial diterpenes

Xiuting Wei, Wenbo Ning, Caitlin A. McCadden, Tyler A. Alsup, Zining Li, Diana P. Łomowska-Keehner, Jordan Nafie, Tracy Qu, Melvin Osei Opoku, Glen R. Gillia, Baofu Xu, Daniel G. Icenhour, Jeffrey D. Rudolf

Version 1 posted 30 August 2024

453

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Organic Chemistry

Working Paper

Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis

Leonidas-Dimitrios Syntrivanis, Shani Levi, Alessandro Prescimone, Dan Thomas Major, Konrad Tiefenbacher

Version 1 posted 26 September 2019

727

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Structure-Guided Product Determination of Bacterial Type II Diterpene Synthases

Emma Stowell, Michelle Ehrenberger, Ya-Lin Lin, Chin-Yuan Chang, Jeffrey Rudolf

Version 2 posted 28 June 2022

412

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Biological and Medicinal Chemistry

Working Paper

Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability

Baofu Xu, Wenbo Ning, Xiuting Wei, Jeffrey Rudolf

Version 1 posted 21 June 2022

253

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Biological and Medicinal Chemistry

Working Paper

First trans-eunicellane terpene synthase in bacteria

Zining Li, Baofu Xu, Volga Kojasoy, Teresa Ortega, Donovon Adpressa, Wenbo Ning, Xiuting Wei, Jamin Liu, Dean Tantillo, Sandra Loesgen, Jeffrey Rudolf

Version 1 posted 13 September 2022

569

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Catalysis

Working Paper

Discovery of a novel eunicellane synthase unveils the relationship between stereochemistry and flexibility among eunicellanes

Jinfeng Li, Bao Chen, Zunyun Fu, Jingjing Mao, Lijun Liu, Xiaochen Chen, Mingyue Zheng, Chang-Yun Wang, Chengyuan Wang, Yue-Wei Guo, Baofu Xu

Version 2 posted 15 December 2023

340

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Biological and Medicinal Chemistry

Working Paper

Avoidance of secondary carbocations, unusual deprotonation, and non-statistical dynamic effects in the cyclization mechanism of the 5/5/5/5-tetracyclic tetraisoquinane skeleton

Xiuting Wei, William DeSnoo, Zining Li, Wenbo Ning, Wang-Yeuk Kong, Jordan Nafie, Dean J. Tantillo, Jeffrey D. Rudolf

Version 1 posted 21 November 2024

0

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7 results in Terpene synthase in Keywords: Terpene synthase

Exploring and expanding the natural chemical space of bacterial diterpenes

Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis

Structure-Guided Product Determination of Bacterial Type II Diterpene Synthases

Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability

First trans-eunicellane terpene synthase in bacteria

Discovery of a novel eunicellane synthase unveils the relationship between stereochemistry and flexibility among eunicellanes

Avoidance of secondary carbocations, unusual deprotonation, and non-statistical dynamic effects in the cyclization mechanism of the 5/5/5/5-tetracyclic tetraisoquinane skeleton

7 results in Keywords: Terpene synthase