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15 results in Keywords: Selective inhibitor, Sirtuins, Structure activity relationship, Molecular dynamics simulations, Electrostatic surface potential, hot-spot, drug discovery

Category: Biological and Medicinal Chemistry
,
Working Paper
, Title:

Development of alkylated hydrazides as highly potent and selective class I HDAC inhibitors with T cell modulatory properties

, Authors: Ping Sun, Jing Wang, Khadija S. Khan, Weiqin Yang, Wai-Lung (Billy) Ng, Nikita Ilment, Matthes Zessin, Emre F. Bülbül, Dina Robaa, Frank Erdmann, Matthias Schmidt, Christophe Romier, Mike Schutkowski, Alfred Sze-Lok Cheng, Wolfgang Sippl
Version 1 posted 15 July 2022
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