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Analytical Chemistry

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Reversible Covalent

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3 results in Keywords: Reversible Covalent

Biological and Medicinal Chemistry

A Mathematical Model for Covalent Proteolysis Targeting Chimeras: Thermodynamics and Kinetics underlying Catalytic Efficiency

Version 1 posted 26 November 2021

1,713

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3

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Organic Chemistry

Thiomethyltetrazines are Reversible Covalent Cysteine Warheads whose Dynamic Behavior can be "Switched off” via Bioorthogonal Chemistry Inside Live Cells

Amanda Tallon, Yingrong Xu, Graham West, Christopher am Ende, Joseph Fox

Version 1 posted 02 May 2023

1,106

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Biological and Medicinal Chemistry

Efficient targeted degradation via reversible and irreversible covalent PROTACs

Ronen Gabizon, Amit Shraga, Paul Gehrtz, Ella Livnah, Yamit Shorer, Neta Gurwicz, Liat Avram, Tamar Unger, Hila Aharoni, Shira Albeck, Alexander Brandis, Ziv Shulman, Ben- Zion Katz, Yair Herishanu, Nir London

Version 2 posted 17 March 2020

2,554

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