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Organic Chemistry

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Rapid Functionalization of Polycarbonates and Polyurethanes via Organocatalyzed SNAr

Eddy Wei Ping Tan, Yi Yan Yang, James Hedrick, Nathaniel Park

Version 1 posted 06 December 2024

194

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Organic Chemistry

Working Paper

Synthesis of Bench-Stable N-Quaternized Ketene N,O-Acetals and Preliminary Evaluation as Reagents in Organic Synthesis

Danielle L. McConnell, Alisha M. Blades, Danielle Gomes Rodrigues, Phoebe V. Keyes, Justin C. Sonberg, Caitlin E. Anthony, Sofia Rachad, Olivia M. Simone, Caroline F. Sullivan, Jonathan D. Shapiro, Christopher C. Williams, Benjamin C. Schafer, Amy Glanzer, Holly Hutchinson, Ashley Thayaparan, Zoe Krevlin, Isabella Bote, Yasin Haffary, Sambat Bhandari, Jack A. Goodman, Max Majireck

Version 2 posted 26 July 2021

1,148

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Organic Chemistry

Working Paper

Machine Learning Meets Mechanistic Modelling for Accurate Prediction of Experimental Activation Energies

Kjell Jorner, Tore Brinck, Per-Ola Norrby, David Buttar

Version 1 posted 05 August 2020

1,127

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Organic Chemistry

Working Paper

A generally applicable quantitative reactivity model for nucleophilic aromatic substitution built from simple descriptors

Jingru Lu, Irina Paci, David Leitch

Version 1 posted 19 July 2022

896

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Organic Chemistry

Working Paper

Development of a Simple Thioetherification of Heteroarene Electrophiles with Broad Scope via a Proton Transfer Dual Ioni-zation Mechanism

Christian Zwick, Jeremy Henle, Shashank Shekhar, Cassie Yang, Yong Zhou, Amanda Wall, Rodger Henry, Matthew Sigman, Maike Eckhoff, Jessica Hoskins, Rafal Swiatowiec, Anna Bay

Version 2 posted 19 December 2024

1,043

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Organic Chemistry

Working Paper

Bicyclic-ammonium-incorporated ylidic nitrogen groups for strong π-electron donation in push–pull benzene π-conjugated systems

Hikaru Fujita, Takanari Arai, Naoto Kuchiki, Munetaka Kunishima

Version 1 posted 21 March 2024

259

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1

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Organic Chemistry

Working Paper

Room temperature nucleophilic aromatic substitution of 2-halopyridinium ketene hemiaminals with sulfur nucleophiles

Jordan Merklin, Beau Sinardo, Max Majireck

Version 1 posted 25 September 2024

195

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Biological and Medicinal Chemistry

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Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)

Stefan Gerstenecker, Lisa Haarer, Martin Schröder, Mark Kudolo, Martin P. Schwalm, Valentin Wydra, Ricardo Serafim, Apirat Chaikuad, Stefan Knapp, Stefan Laufer, Matthias Gehringer

Version 1 posted 15 July 2021

363

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Organic Chemistry

Working Paper

A revised synthesis of 6-alkoxy-2-aminopurines with late-stage convergence allowing for increased molecular complexity

Lavleen Mader, John Hayward, Lisa Porter, John Trant

Version 1 posted 06 May 2022

310

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Organic Chemistry

Working Paper

Bench-stable 2-halopyridinium ketene hemiaminals as new reagents for the synthesis of 2-aminopyridine derivatives

Isabelle Bote, Zoe Krevlin, Maria Christina Crespo, Sudchananya Udomphan, Carolyn Levin, Christie Lam, Amy Glanzer, Holly Hutchinson, Alisha Blades, Danielle McConnell, Crystal Lin, John Frank, William Strutton, Jordan Merklin, Beau Sinardo, Khady Gueye, Karly Leiman, Ashley Thayaparan, Joel Adade, Nestor Martinez, Wesley Kramer, Max Majireck

Version 2 posted 01 August 2024

703

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Refine Search

14 results in Nucleophilic Aromatic Substitution in Keywords: Nucleophilic Aromatic Substitution

Rapid Functionalization of Polycarbonates and Polyurethanes via Organocatalyzed SNAr

Synthesis of Bench-Stable N-Quaternized Ketene N,O-Acetals and Preliminary Evaluation as Reagents in Organic Synthesis

Machine Learning Meets Mechanistic Modelling for Accurate Prediction of Experimental Activation Energies

A generally applicable quantitative reactivity model for nucleophilic aromatic substitution built from simple descriptors

Development of a Simple Thioetherification of Heteroarene Electrophiles with Broad Scope via a Proton Transfer Dual Ioni-zation Mechanism

Bicyclic-ammonium-incorporated ylidic nitrogen groups for strong π-electron donation in push–pull benzene π-conjugated systems

Room temperature nucleophilic aromatic substitution of 2-halopyridinium ketene hemiaminals with sulfur nucleophiles

Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)

A revised synthesis of 6-alkoxy-2-aminopurines with late-stage convergence allowing for increased molecular complexity

Bench-stable 2-halopyridinium ketene hemiaminals as new reagents for the synthesis of 2-aminopyridine derivatives

14 results in Keywords: Nucleophilic Aromatic Substitution