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Biological and Medicinal Chemistry

Working Paper

N-terminal cysteine as minimalistic handle for dual, site-selective bioconjugation: application to an anti-HER2 affibody reveals synergy of two conjugated drugs

Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, Carlo Pifferi, Vincent Aucagne

Version 2 posted 15 May 2023

552

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Biological and Medicinal Chemistry

Working Paper

One-Pot Chemical Protein Synthesis Utilizing Fmoc-Masked Selenazolidine to Address the Redox Functionality of Human Selenoprotein F

Zhenguang Zhao, Reem Mousa, Norman Metanis

Version 1 posted 19 January 2022

188

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Catalysis

Working Paper

Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

Florent kerdraon, Gemma Bogard, Benoît Snella, Hervé Drobecq, Muriel Pichavant, Vangelis Agouridas, Oleg Melnyk

Version 1 posted 11 February 2021

351

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Biological and Medicinal Chemistry

Working Paper

Chemical Synthesis of Shiga Toxin Subunit B Using a Next-Generation Traceless “Helping Hand” Solubilizing Tag

James Fulcher, Mark Petersen, riley giesler, Zachary Cruz, debra eckert, J. Nicholas Francis, eric kawamoto, Michael Jacobsen, Michael Kay

Version 2 posted 23 September 2019

784

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Biological and Medicinal Chemistry

Working Paper

A Cysteine Selenosulfide Redox Switch for Protein Chemical Synthesis

Vincent Diemer, Nathalie Ollivier, Bérénice Leclercq, Hervé Drobecq, Jérôme Vicogne, Vangelis Agouridas, Oleg Melnyk

Version 2 posted 26 February 2020

739

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Biological and Medicinal Chemistry

Working Paper

A Straightforward Methodology to Overcome Solubility Challenges for N-Terminal Cysteinyl Peptide Segments Used in Native Chemical Ligation

Skander Abboud, El hadji Cisse, Michel Doudeau, Hélène Bénédetti, Vincent AUCAGNE

Version 1 posted 03 November 2020

400

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Biological and Medicinal Chemistry

Working Paper

Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)

Patrick Erickson, James Fulcher, Michael Kay

Version 1 posted 13 July 2020

1,051

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Catalysis

Working Paper

Electrostatic Assistance of 4-Mercaptophenylacetic acid catalyzed Native Chemical Ligation

Nathalie Ollivier, Eliott Roy, Rémi Desmet, Vangelis Agouridas, Vincent Diemer, Oleg Melnyk

Version 1 posted 10 March 2023

334

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1

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Organic Chemistry

Working Paper

Thiazolidine Deprotection by 2-Aminobenzamide-Based Aldehyde Scavenger for One-Pot Multiple Peptide Ligation

Koki Nakatsu, Hitoshi Murakami, Gosuke Hayashi, Akimitsu Okamoto

Version 1 posted 03 June 2021

882

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Biological and Medicinal Chemistry

Working Paper

Selenolysine: A New Tool for Traceless Isopeptide Bond Formation

Rebecca Notis Dardashti, Shailesh Kumar, Shawn M. Sternisha, Post Sai Reddy, Brian G. Miller, Norman Metanis

Version 1 posted 24 December 2019

574

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Refine Search

23 results in Native Chemical Ligation in Keywords: Native Chemical Ligation

N-terminal cysteine as minimalistic handle for dual, site-selective bioconjugation: application to an anti-HER2 affibody reveals synergy of two conjugated drugs

One-Pot Chemical Protein Synthesis Utilizing Fmoc-Masked Selenazolidine to Address the Redox Functionality of Human Selenoprotein F

Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

Chemical Synthesis of Shiga Toxin Subunit B Using a Next-Generation Traceless “Helping Hand” Solubilizing Tag

A Cysteine Selenosulfide Redox Switch for Protein Chemical Synthesis

A Straightforward Methodology to Overcome Solubility Challenges for N-Terminal Cysteinyl Peptide Segments Used in Native Chemical Ligation

Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)

Electrostatic Assistance of 4-Mercaptophenylacetic acid catalyzed Native Chemical Ligation

Thiazolidine Deprotection by 2-Aminobenzamide-Based Aldehyde Scavenger for One-Pot Multiple Peptide Ligation

Selenolysine: A New Tool for Traceless Isopeptide Bond Formation

23 results in Keywords: Native Chemical Ligation