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Biological and Medicinal Chemistry

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Organic Chemistry

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Theoretical and Computational Chemistry

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MedChem

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4 results in Keywords: MedChem

Biological and Medicinal Chemistry

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Christian Steinebach, Izidor Sosič, Aleša Bricelj, Arunima Murgai, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Annika Schmidt, Patricia Lemnitzer, Finn K. Hansen, Michael Gütschow, Jan Krönke, Marcus D. Hartmann

Version 1 posted 21 April 2023

1,597

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1

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Biological and Medicinal Chemistry

Expanding the PROTAC Toolbox: Targeted Degradation of the Deubiquitinase USP7 in Cancer

Arunima Murgai, Izidor Sosič, Martina Gobec, Patricia Lemnitzer, Matic Proj, Sophie Wittenburg, Michael Gütschow, Jan Krönke, Christian Steinebach

Version 1 posted 13 April 2022

1,274

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Theoretical and Computational Chemistry

Learning chemical intuition from humans in the loop

Oh-Hyeon Choung, Riccardo Vianello, Marwin Segler, Nikolaus Stiefl, José Jiménez-Luna

Version 2 posted 16 March 2023

3,770

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Organic Chemistry

Constructing All-Carbon Quaternary Centers from Ketones via Titanacyclobutanes: Rapid Access to Azaspiro[3.n]alkanes

Tyler Weinhold, James Law, James Frederich

Version 1 posted 15 May 2023

911

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