Search

Biological and Medicinal Chemistry

Working Paper

Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently

John Eaton, Richard A. Ruberto, Anneke Kramm, Vasanthi S. Viswanathan, Stuart Schreiber

Version 1 posted 23 January 2019

852

Downloads

Biological and Medicinal Chemistry

Working Paper

Structure–activity Relationships of Glutathione Peroxidase 4 Inhibitor Warheads

John Eaton, Laura Furst, Luke Cai, Vasanthi S. Viswanathan, Stuart L. Schreiber

Version 1 posted 20 April 2020

892

Downloads

Biological and Medicinal Chemistry

Working Paper

PDTAC: Targeted photodegradation of GPX4 triggers Ferroptosis and potent antitumor immunity

Sijin Liu, Xi Zhao, Sufang Shui, Biao Wang, Yingxian Cui, Tairan Yuwen, Suwei Dong, Guoquan Liu

Version 1 posted 31 May 2022

461

Downloads

Biological and Medicinal Chemistry

Working Paper

BASHY Dyes Are Highly Efficient Lipid Droplet-targeting Photosensitizers That Induce Ferroptosis Through Lipid Peroxidation

Maria Silva, Yiyi Zhang, Robin Vinck, Fábio Santos, João António, Lisa Gourdon-Grünewaldt, Charlotte Zaouter, Annie Castonguay, Shunmoogum Patten, Kevin Cariou, Francisco Boscá, Francisco Nájera, Jesús Arteaga, Gilles Gasser, Uwe Pischel, Pedro Gois

Version 2 posted 11 October 2023

296

Downloads

Biological and Medicinal Chemistry

Working Paper

Enzymatically Catalyzed Molecular Aggregation

Wen-Jin Wang, Rongyuan Zhang, Liping Zhang, Liang Hao, Xu-Min Cai, Qian Wu, Zijie Qiu, Jing Feng, Shaojuan Wang, Parvej Alam, Guoqing Zhang, Zheng Zhao, Ben Zhong Tang

Version 2 posted 29 February 2024

280

Downloads

Biological and Medicinal Chemistry

Working Paper

Identification of PLK1 as the Target of Tubocapsenolide A for the Activation of Colorectal Cancer Ferroptosis by PROTAC Technology

Yueying Yang, Yang Liu, Lu Wang, Jing Liang, Hongyan Zhang, Zhiruo Zhang, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Wenyi Wei, Hua Li, Lixia Chen

Version 1 posted 08 October 2024

219

Downloads

Biological and Medicinal Chemistry

Working Paper

Tunable Cysteine-Targeting Electrophilic Hetero-Aromatic Warheads Induce Ferroptosis

Endri Karaj, Shaimaa H. Sindi, Nishanth Kuganesan, Lalith Perera, William Taylor, L. M. Viranga Tillekeratne

Version 1 posted 11 April 2022

982

Downloads

Biological and Medicinal Chemistry

Working Paper

Differential contributions of distinct free radical peroxidation mechanisms to the induction of ferroptosis

Quynh Do, Rutan Zhang, Gavin Hooper, Libin Xu

Version 1 posted 09 December 2022

249

Downloads

Biological and Medicinal Chemistry

Working Paper

LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode

Darius Mazhari Dorooee, Severine Ravez, Didier Vertommen, Nicolas Renault, Nicolas Papadopoulos, Romain Marteau, Emeline Charnelle, Karine Porte, Alexandre Gobert, Nathalie Hennuyer, Gaetan Herinckx, Bart Staels, Patricia Melnyk, Stefan Constantinescu, Raphael Frederick, Jamal El Bakali

Version 1 posted 08 July 2024

199

Downloads

Organic Chemistry

Working Paper

NIR emissive probe for fluorescence turn-on based dead cell sorting and in-vivo viscosity mapping in C. elegans

Goraksha T. Sapkal, Farhan Anjum, Abdul Salam, Bodhidipra Mukherjee, Shilpa Chandra, Purabi Bala, Richa Garg, Shagun Sharma, Kush Kaushik, Chayan Kanti Nandi

Version 1 posted 01 November 2024

91

Downloads

Refine Search

11 results in Ferroptosis in Keywords: Ferroptosis

Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently

Structure–activity Relationships of Glutathione Peroxidase 4 Inhibitor Warheads

PDTAC: Targeted photodegradation of GPX4 triggers Ferroptosis and potent antitumor immunity

BASHY Dyes Are Highly Efficient Lipid Droplet-targeting Photosensitizers That Induce Ferroptosis Through Lipid Peroxidation

Enzymatically Catalyzed Molecular Aggregation

Identification of PLK1 as the Target of Tubocapsenolide A for the Activation of Colorectal Cancer Ferroptosis by PROTAC Technology

Tunable Cysteine-Targeting Electrophilic Hetero-Aromatic Warheads Induce Ferroptosis

Differential contributions of distinct free radical peroxidation mechanisms to the induction of ferroptosis

LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode

NIR emissive probe for fluorescence turn-on based dead cell sorting and in-vivo viscosity mapping in C. elegans

11 results in Keywords: Ferroptosis