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11 results in Keywords: Enzyme inhibition

Biological and Medicinal Chemistry

Working Paper

7-Aminoalkoxy-Quinazolines from Epigenetic Focused Libraries are Potent and Selective Inhibitors of DNA Methyltransferase 1

José L. Medina-Franco, Edgar López-López, Liliam P. Martínez-Fernández

Version 1 posted 08 March 2022

228

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Organic Chemistry

Working Paper

Synthesis and Evaluation of α-Amylase and Lipase Inhibitory Activities of Synthetic Coumarin Derivatives

shivaprasad shetty Mangalpady, NV Anil, Anil Kumar HS

Version 1 posted 25 February 2019

689

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Biological and Medicinal Chemistry

Working Paper

Targeted Chemoenzymatic Synthesis of Sugar Nucleotide Probes Reveal an Inhibitor of the GDP-D-Mannose Dehydrogenase from Pseudomonas Aeruginosa

Laura Beswick, Eleni Dimitriou, Sanaz Ahmadipour, Ayesha Zafar, Martin Rejzek, Johannes Reynisson, Robert Field, Gavin Miller

Version 1 posted 27 May 2020

540

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Biological and Medicinal Chemistry

Working Paper

A Steady-State Algebraic Model for the Time Course of Covalent Enzyme Inhibition

Petr Kuzmic

Version 3 posted 06 August 2020

780

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Biological and Medicinal Chemistry

Working Paper

Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase

Alex H. Y. Chan, Terence C. S. Ho, Kwasi Agyei-Owusu, Finian James Leeper

Version 1 posted 06 October 2022

105

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Biological and Medicinal Chemistry

Working Paper

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

Alex H. Y. Chan, Terence C. S. Ho, Imam Fathoni, Rawia Hamid, Anna K. H. Hirsch, Kevin J. Saliba, Finian James Leeper

Version 1 posted 17 January 2024

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Biological and Medicinal Chemistry

Working Paper

Peptidomimetic small-molecule inhibitors of 3CLPro activity and Spike-ACE2 interaction: towards dual-action molecules against Coronavirus infections

Filomena Tedesco, Lorenzo Calugi, Elena Lenci, Andrea Trabocchi

Version 1 posted 18 April 2022

229

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Analytical Chemistry

Working Paper

The Steadfast Au@Pt Soldier: Peroxide-Tolerant Nanozyme for Signal Enhancement in Lateral Flow Immunoassay of Peroxidase-Containing Samples

Vasily Panferov, Irina V. Safenkova, Anatoly V. Zherdev, Boris B. Dzantiev

Version 1 posted 23 September 2020

775

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Biological and Medicinal Chemistry

Working Paper

A common mechanism links activities of butyrate in the colon

Mohit S. Verma, Michael J. Fink, Gabriel L Salmon, Nadine Fornelos, Takahiro E. Ohara, Stacy S. Ryu, Hera Vlamakis, Ramnik J. Xavier, Thaddeus S. Stappenbeck, George M. Whitesides

Version 1 posted 19 September 2017

854

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Biological and Medicinal Chemistry

Working Paper

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

Alex H. Y. Chan, Terence C. S. Ho, Rimsha Irfan, Rawia A. A. Hamid, Emma S. Rudge, Amjid Iqbal, Alex Turner, Anna K. H. Hirsch, Finian James Leeper

Version 2 posted 20 February 2023

187

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11 results in Enzyme inhibition in Keywords: Enzyme inhibition

7-Aminoalkoxy-Quinazolines from Epigenetic Focused Libraries are Potent and Selective Inhibitors of DNA Methyltransferase 1

Synthesis and Evaluation of α-Amylase and Lipase Inhibitory Activities of Synthetic Coumarin Derivatives

Targeted Chemoenzymatic Synthesis of Sugar Nucleotide Probes Reveal an Inhibitor of the GDP-D-Mannose Dehydrogenase from Pseudomonas Aeruginosa

A Steady-State Algebraic Model for the Time Course of Covalent Enzyme Inhibition

Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

Peptidomimetic small-molecule inhibitors of 3CLPro activity and Spike-ACE2 interaction: towards dual-action molecules against Coronavirus infections

The Steadfast Au@Pt Soldier: Peroxide-Tolerant Nanozyme for Signal Enhancement in Lateral Flow Immunoassay of Peroxidase-Containing Samples

A common mechanism links activities of butyrate in the colon

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

11 results in Keywords: Enzyme inhibition