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Biological and Medicinal Chemistry

(3)

Theoretical and Computational Chemistry

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Last 3 years

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Electrophiles

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3 results in Keywords: Electrophiles

Biological and Medicinal Chemistry

oxSTEF reagents are tunable and versatile electrophiles for selective disulfide-rebridging of native proteins

Marija Nisavic, Gustav Wørmer, Cecilie Nielsen, Sofie Jeppesen, Johan Palmfeldt, Thomas Poulsen

Version 1 posted 03 October 2022

665

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Biological and Medicinal Chemistry

Systematic exploration of privileged warheads for covalent kinase drug discovery

Zheng Zhao, Philip E. Bourne

Version 1 posted 16 August 2022

1,776

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1

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Biological and Medicinal Chemistry

The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21

Esben Svenningsen, Rasmus Ottosen, Katrine Jørgensen, Marija Nisavic, Camilla Larsen, Bente Hansen, Yong Wang, Kresten Lindorff-Larsen, Thomas Tørring, Stephan Hacker, Johan Palmfeldt, Thomas Poulsen

Version 1 posted 01 July 2022

353

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