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  • E3 ligase
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9 results in Keywords: E3 ligase

Category: Biological and Medicinal Chemistry
,
Working Paper
, Title:

Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1alpha (HIF-1alpha) Stabilizers

, Authors: Lan Phuong Vu, Claudia Diehl, Ryan Casement, Adam Bond, Christian Steinebach, Nika Strasek, Alesa Bricelj, Andrej Perdih, Gregor Schnakenburg, Izidor Sosic, Alessio Ciulli, Michael Gutschow
Version 2 posted 01 August 2023
1,204
Downloads
Category: Biological and Medicinal Chemistry
,
Working Paper
, Title:

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

, Authors: Satomi Imaide, Kristin M. Riching, Nikolai Makukhin, Vesna Vetma, Claire Whitworth, Scott J. Hughes, Nicole Trainor, Sarah D. Mahan, Nancy Murphy, Angus Cowan, Kwok-Ho Chan, Conner Craigon, Andrea Testa, Chiara Maniaci, Marjeta Urh, Danette L. Daniels, Alessio Ciulli
Version 2 posted 20 October 2021
4,582
Downloads
Category: Biological and Medicinal Chemistry
,
Working Paper
, Title:

Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1

, Authors: Simon Ng, Alexander Brueckner, Soheila Bahmanjah, Qiaolin Deng, Jennifer Johnston, Lan Ge, Ruchia Duggal, Bahanu Habulihaz, Benjamin Barlock, Sookhee Ha, Ahmad Sadruddin, Constance Yeo, Corey Strickland, Andrea Peier, Brian Henry, Edward Sherer, Anthony Partridge
Version 1 posted 22 December 2021
1,190
Downloads
2
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