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Multigram Synthesis of 4,4-disubstituted-3-oxopyrrolidones – efficient starting material for diverse 3 functionalized pyrrolidones

Semen Bondarenko, Anatolii Fedorchenko, Pavlo Novosolov, Oleksandr Marchenko, Anton Hanopolskyi, Yulian Volovenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 17 January 2024

219

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1

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Organic Chemistry

Working Paper

Convenient one-pot synthesis and biological evaluation of novel 3,5-dimethyl-1H-pyrazole-1-carbothiohydrazide derivatives as new anti-tumor agents against both liver carcinoma (HepG2) and lung carcinoma (A549) cell lines

Marwa Fouad, Mahmoud Elaasser

Version 1 posted 22 December 2023

158

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Organic Chemistry

Working Paper

Mechanistic basis for the Iridium-Catalyzed Enantioselective Al-lylation of Alkenyl Boronates

Colton Davis, Joseph Ready

Version 1 posted 15 March 2022

369

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Biological and Medicinal Chemistry

Working Paper

Chemoselective Esterification of Natural and Prebiotic 1,2-Amino Alcohol Amphiphiles in Water

Ahanjit Bhattacharya, Lalita Tanwar, Alessandro Fracassi, Roberto Brea, Marta Salvador-Castell, Satyam Khanal, Sunil Sinha, Neal Devaraj

Version 1 posted 20 June 2023

321

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Organometallic Chemistry

Working Paper

Introducing Type Ⅲ Metal Complex-Stabilized Olefin Radical Cation Induced Addition: A New Mechanism for Palladium-Catalyzed Wacker-Type Oxidation of Terminal Alkenes

Liuqun Gu

Version 1 posted 05 March 2024

242

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Biological and Medicinal Chemistry

Working Paper

Synthesis and evaluation of tetrahydropyrrolo[1,2-a]quinolin-1(2H)-ones as new tubulin polymerization inhibitors

Mikhail N. Anisimov, Maksim A. Boichenko, Vitaly V. Shorokhov, Julia N. Borzunova, Marina Janibekova, Vadim V. Mustyatsa, Ilya A. Lifshits, Andrey Yu. Plodukhin, Ivan A. Andreev, Nina K. Ratmanova, Sergey S. Zhokhov, Elena A. Tarasenko, Ivan A. Vorobjev, Igor V. Trushkov, Olga A. Ivanova, Nikita Gudimchuk

Version 1 posted 10 June 2024

131

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Organic Chemistry

Working Paper

Electrophilic Halogenation of Allenoates and 3-Alkynoates: Syn-thesis of 1,4-Dicarbonyl 3-(E)-Haloalkenes and Mechanistic Investigations

Paru Jamwal, Yumnam Nganthoinganbi, Ming-Kang Tsai, Ramani Gurubrahamam

Version 1 posted 11 September 2024

179

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Catalysis

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Dearomative Selective Reduction of Structurally Diverse N-Heteroarenes Enabled by Titanium Catalysis

Kishore Natte, Tarun Bhatt, Suman Vadithya, Mridula Choudhary, Saurabh Kumar Singh

Version 1 posted 04 November 2024

302

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Materials Chemistry

Working Paper

Enigmatic Alternatives for Epoxides in Graphene Oxide

Gaurav Jhaa, Pattath D. Pancharatna, Musiri M. Balakrishnarajan

Version 1 posted 22 May 2023

147

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Organic Chemistry

Working Paper

NHCs and Visible Light-mediated Photoredox Co-catalyzed Radical 1,2-Dicarbonylation of Alkenes for 1,4-Diketones

Lihong Wang, Jiaqiong Sun, Jiuli Xia, Mingrui Li, Lianjin Zhang, Ruiyang Ma, Guangfan Zheng, Qian Zhang

Version 1 posted 27 December 2021

644

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2

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16 results in 1, 3, 4-Oxadiazoles in Keywords: 1, 3, 4-Oxadiazoles

Multigram Synthesis of 4,4-disubstituted-3-oxopyrrolidones – efficient starting material for diverse 3 functionalized pyrrolidones

Convenient one-pot synthesis and biological evaluation of novel 3,5-dimethyl-1H-pyrazole-1-carbothiohydrazide derivatives as new anti-tumor agents against both liver carcinoma (HepG2) and lung carcinoma (A549) cell lines

Mechanistic basis for the Iridium-Catalyzed Enantioselective Al-lylation of Alkenyl Boronates

Chemoselective Esterification of Natural and Prebiotic 1,2-Amino Alcohol Amphiphiles in Water

Introducing Type Ⅲ Metal Complex-Stabilized Olefin Radical Cation Induced Addition: A New Mechanism for Palladium-Catalyzed Wacker-Type Oxidation of Terminal Alkenes

Synthesis and evaluation of tetrahydropyrrolo[1,2-a]quinolin-1(2H)-ones as new tubulin polymerization inhibitors

Electrophilic Halogenation of Allenoates and 3-Alkynoates: Syn-thesis of 1,4-Dicarbonyl 3-(E)-Haloalkenes and Mechanistic Investigations

Dearomative Selective Reduction of Structurally Diverse N-Heteroarenes Enabled by Titanium Catalysis

Enigmatic Alternatives for Epoxides in Graphene Oxide

NHCs and Visible Light-mediated Photoredox Co-catalyzed Radical 1,2-Dicarbonylation of Alkenes for 1,4-Diketones

16 results in Keywords: 1, 3, 4-Oxadiazoles