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Protein-Templated Hit Identification via an Ugi Four-Component Reaction

Federica Mancini, M. Yagiz Unver, Walid Elgaher, Varsha R. Jumde, Alaa Alhayek, Peer Lukat, jennifer herrmann, Martin D. Witte, Matthias Köck, Wulf Blankenfeldt, rolf müller, Anna K.H. Hirsch

Version 1 posted 31 January 2020

466

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Biological and Medicinal Chemistry

Working Paper

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Eleonora Diamanti, Inda Setyawati, Spyridon Bousis, Paulo C. T. Souza, leticia mojas, lotteke Swier, Jörg Haupenthal, Paddy Gibson, carsten volz, weronika stanek, manuel Jaeger, jennifer herrmann, Siewert Marrink, jan-willem veening, rolf müller, dirk J. slotboom, Anna K.H. Hirsch

Version 2 posted 01 December 2021

1,106

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4

Citations

Analytical Chemistry

Working Paper

Expanding the Scope of Detectable Microbial Natural Products by Complementary Analytical Methods and Cultivation Systems

Chantal Bader, Patrick Haack, Fabian Panter, Daniel Krug, Rolf Müller

Version 1 posted 19 June 2020

2,408

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Biological and Medicinal Chemistry

Working Paper

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Jelena Konstantinovic, Andreas M. Kany, Alaa Alhayek, Ahmed S. Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf W. Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch

Version 1 posted 24 April 2023

279

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Biological and Medicinal Chemistry

Working Paper

Sandacrabins – Structurally unique antiviral RNA polymerase inhibitors from a rare myxobacterium

Chantal Bader, Fabian Panter, Ronald Garcia, Egor Tchesnokov, Sibylle Haid, Christine Walt, Cathrin Spröer, Alexander Kiefer, Matthias Götte, Jörg Overmann, Thomas Pietschmann, Rolf Müller

Version 1 posted 15 October 2021

396

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Biological and Medicinal Chemistry

Working Paper

New Genetically Engineered Derivatives of Antibacterial Darobac-tins Underpin their Potential for Antibiotic Development

Carsten E. Seyfert, Alison V. Müller, Danica J. Walsh, Joy Birkelbach, Andreas M. Kany, Christoph Porten, Biao Yuan, Daniel Krug, Jennifer Herrmann, Thomas C. Marlovits, Anna K. H. Hirsch, Rolf Müller

Version 1 posted 11 September 2023

202

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1

Citations

Analytical Chemistry

Working Paper

Supercritical Fluid Extraction Enhances Discovery of Secondary Metabolites from Myxobacteria

Chantal Bader, Markus Neuber, Fabian Panter, Daniel Krug, Rolf Müller

Version 1 posted 13 July 2020

859

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Biological and Medicinal Chemistry

Working Paper

Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway

Asfandyar Sikandar, Maria Lopatniuk, Andriy Luzhetskyy, Rolf Müller, Jesko Koehnke

Version 1 posted 12 January 2022

421

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Biological and Medicinal Chemistry

Working Paper

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

Di Zhu, Sandra Johannsen, Tiziana Masini, Céline Simonin, Jörg Haupenthal, Boris Illarionov, Anastasia Andreas, Mahendra Awale, Robin M. Gierse, Tridia van der Laan, Ramon van der Vlag, Rita Nasti, Mael Poizat, Eric Buhler, Norbert Reiling, Rolf Müller, Markus Fischer, Jean-Louis Reymond, Anna K. H. Hirsch

Version 2 posted 11 April 2022

331

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Biological and Medicinal Chemistry

Working Paper

Activity and cryo-EM structure guided biosynthetic pathway engineering yields non-natural Darobactin antibiotics with superior activity against Gram-negative pathogens

Carsten E. Seyfert, Christoph Porten, Biao Yuan, Selina Deckarm, Fabian Panter, Chantal D. Bader, Janetta Coetzee, Felix Deschner, Kamaleddin H. M. E. Tehrani, Paul G. Higgins, Harald Seifert, Thomas Marlovits, Jennifer Herrmann, Rolf Müller

Version 2 posted 26 September 2022

756

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2

Citations

Refine Search

17 results in rolf müller in Authors: rolf müller

Protein-Templated Hit Identification via an Ugi Four-Component Reaction

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Expanding the Scope of Detectable Microbial Natural Products by Complementary Analytical Methods and Cultivation Systems

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Sandacrabins – Structurally unique antiviral RNA polymerase inhibitors from a rare myxobacterium

New Genetically Engineered Derivatives of Antibacterial Darobac-tins Underpin their Potential for Antibiotic Development

Supercritical Fluid Extraction Enhances Discovery of Secondary Metabolites from Myxobacteria

Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

Activity and cryo-EM structure guided biosynthetic pathway engineering yields non-natural Darobactin antibiotics with superior activity against Gram-negative pathogens

17 results in Authors: rolf müller