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Catalysis

Working Paper

Effects of the Y432S Cancer-Associated Variant on the Reaction Mechanism of Human DNA Polymerase κ

Yazdan Maghsoud, Arkanil Roy, Emmett M. Leddin, G. Andrés Cisneros

Version 1 posted 28 February 2024

220

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Theoretical and Computational Chemistry

Working Paper

Impact of Remdesivir Incorporation Along the Primer Strand on SARS-CoV-2 RNA-dependent RNA polymerase

Sehr Naseem-Khan, Madison B. Berger, Emmett M. Leddin, Yazdan Maghsoud, G. Andrés Cisneros

Version 2 posted 29 March 2022

357

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Catalysis

Working Paper

Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate off-Target Effects

Yazdan Maghsoud, Vindi M. Jayasinghe-Arachchige, Pratibha Kumari, G. Andrés Cisneros, Jin Liu

Version 2 posted 26 June 2023

528

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Theoretical and Computational Chemistry

Working Paper

Computational Investigation of a Series of Small Molecules as Lead Compounds for Lysyl hydroxylase-2 (LH2) Inhibition

Yazdan Maghsoud, Erik Antonio Vázquez-Montelongo, Xudong Yang, Chengwen Liu, Zhifeng Jing, Juhoon Lee, Matthew Harger, Ally K. Smith, Miguel Espinoza, Hou-Fu Guo, Jonathan M. Kurie, Kevin N. Dalby, Pengyu Ren, G. Andrés Cisneros

Version 1 posted 01 September 2022

225

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Biological and Medicinal Chemistry

Working Paper

1,3-diketone analogs as selective lysyl hydroxylase 2 (LH2) antagonists

Juhoon Lee, Hou-fu Guo, Yazdan Maghsoud, Erik Antonio Vázquez-Montelongo, Zhifeng Jing, Shike Wang, Rachel M. Sammons, Eun Jeong Cho, Pengyu Ren, G. Andrés Cisneros, Jonathan M. Kurie, Kevin N. Dalby

Version 1 posted 01 December 2022

322

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2

Citations

Catalysis

Working Paper

Computational Insights into the Inhibition Mechanism of Xanthine Oxidoreductase by Oxipurinol

Yazdan Maghsoud, Chao Dong, G. Andrés Cisneros

Version 2 posted 17 April 2023

265

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Theoretical and Computational Chemistry

Working Paper

Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat

Yazdan Maghsoud, Chao Dong, G. Andrés Cisneros

Version 1 posted 21 November 2022

380

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Theoretical and Computational Chemistry

Review

Computational Studies on the Functional and Structural Impact of Pathogenic Mutations in Enzymes

Upeksha C. Dissanayake, Arkanil Roy, Yazdan Maghsoud, Sarthi Polara, Tanay Debnath, G. Andrés Cisneros

Version 1 posted 12 November 2024

113

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Refine Search

8 results in Yazdan Maghsoud in Authors: Yazdan Maghsoud

Effects of the Y432S Cancer-Associated Variant on the Reaction Mechanism of Human DNA Polymerase κ

Impact of Remdesivir Incorporation Along the Primer Strand on SARS-CoV-2 RNA-dependent RNA polymerase

Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate off-Target Effects

Computational Investigation of a Series of Small Molecules as Lead Compounds for Lysyl hydroxylase-2 (LH2) Inhibition

1,3-diketone analogs as selective lysyl hydroxylase 2 (LH2) antagonists

Computational Insights into the Inhibition Mechanism of Xanthine Oxidoreductase by Oxipurinol

Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat

Computational Studies on the Functional and Structural Impact of Pathogenic Mutations in Enzymes

8 results in Authors: Yazdan Maghsoud