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Biological and Medicinal Chemistry

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William Pomerantz

6 results in Authors: William Pomerantz

Biological and Medicinal Chemistry

Potent and Selective N-Terminal BRD4 Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water Displacement

Huarui Cui, Anand Divakaran, Anil K. Pandey, Jorden A. Johnson, huda zahid, zachary hoell, mikael ellingson, ke shi, Hideki Aihara, Daniel A. Harki, william pomerantz

Version 1 posted 23 April 2020

563

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Biological and Medicinal Chemistry

Design of Class I/IV Bromodomain-Targeting Degraders for Chromatin Remodeling Complexes

Huda Zahid, Jeff Costello, Jennifer Kimbrough, Marisa Actis, Zoran Rankovic, William Pomerantz

Version 1 posted 05 October 2022

453

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Biological and Medicinal Chemistry

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain

Michael Brand, James Clayton, Mustafa Moroglu, Matthias Schiedel, Sarah Picaud, Joseph Bluck, Anna Skwarska, Anthony Chan, Corentine Laurin, Amy Scorah, Larissa See, Timothy Rooney, Oleg Fedorov, Gabriella Perell, Prakriti Kalra, Wilian Cortopassi, Kirsten Christensen, Richard Cooper, Robert Paton, William Pomerantz, Philip Biggin, Ester M. Hammond, Panagis Filippakopoulos, Stuart Conway

Version 1 posted 06 April 2020

617

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3

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Biological and Medicinal Chemistry

Efficacy and toxicity analysis of selective BET bromodomain inhibitors in models of inflammatory liver disease

Luke Doskey, Cole Scholtz, Nora Vail, Shalil Khanal, Amani Lee, Sai Giridhar Sarma Kandanur, Zachariah Hoell, Amelia Huehls, Mohamed Issa, Enis Kostallari, Sheng Cao, Joel Reid, Harmeet Malhi, Vijay Shah, william pomerantz

Version 1 posted 24 October 2024

60

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Biological and Medicinal Chemistry

Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small Molecule Inhibitors

Caroline Buchholz, Molly Sneddon, Joseph McPherson, Sourav Das, Clifford Gee, Michael Grillo, Sergio Chai, Richard Lee, Taosheng Chen, Dan Harki, Anang Shelat, William Pomerantz

Version 1 posted 14 August 2023

278

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Biological and Medicinal Chemistry

Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader

Anand Divakaran, Huda Zahid, Wenwei Lin, Taosheng Chen, Dan Harki, william pomerantz

Version 1 posted 12 October 2021

684

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