Search

6 results in Authors: Terence C. S. Ho

Biological and Medicinal Chemistry

Working Paper

Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes

Alex H. Y. Chan, Terence C. S. Ho, Finian James Leeper

Version 1 posted 30 May 2023

Downloads

Biological and Medicinal Chemistry

Working Paper

Triazole-Based Thiamine Analogues as Inhibitors of Thiamine Pyrophosphate-Dependent Enzymes: 1,3-Dicarboxylate for Metal Binding

Terence C. S. Ho, Alex H. Y. Chan, Finian James Leeper

Version 1 posted 09 May 2024

Downloads

Biological and Medicinal Chemistry

Working Paper

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

Alex H. Y. Chan, Terence C. S. Ho, Imam Fathoni, Rawia Hamid, Anna K. H. Hirsch, Kevin J. Saliba, Finian James Leeper

Version 1 posted 17 January 2024

131

Downloads

Biological and Medicinal Chemistry

Working Paper

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

Alex H. Y. Chan, Terence C. S. Ho, Rimsha Irfan, Rawia A. A. Hamid, Emma S. Rudge, Amjid Iqbal, Alex Turner, Anna K. H. Hirsch, Finian James Leeper

Version 2 posted 20 February 2023

232

Downloads

Biological and Medicinal Chemistry

Working Paper

Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase

Alex H. Y. Chan, Terence C. S. Ho, Kwasi Agyei-Owusu, Finian James Leeper

Version 1 posted 06 October 2022

122

Downloads

Biological and Medicinal Chemistry

Working Paper

Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues

Alex H. Y. Chan, Terence C. S. Ho, Imam Fathoni, Rebecca Pope, Kevin J. Saliba, Finian James Leeper

Version 1 posted 25 January 2023

175

Downloads

Search

Refine Search

6 results in Terence C. S. Ho in Authors: Terence C. S. Ho

Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes

Triazole-Based Thiamine Analogues as Inhibitors of Thiamine Pyrophosphate-Dependent Enzymes: 1,3-Dicarboxylate for Metal Binding

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase

Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues

6 results in Authors: Terence C. S. Ho