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Tatu Pantsar

3 results in Authors: Tatu Pantsar

Theoretical and Computational Chemistry

Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations

Renne Leini, Jonas Kapp, Kari Kopra, Tatu Pantsar

Version 2 posted 27 March 2025

698

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Theoretical and Computational Chemistry

In silico Evaluation of the Thr58-associated Conserved Water with KRAS Switch-II Pocket Binders

Renne Leini, Tatu Pantsar

Version 1 posted 22 November 2022

707

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Analytical Chemistry

Beyond KRAS(G12C): biochemical and computational characterization of sotorasib and adagrasib binding specificity and the critical role of H95 and Y96

Randa Mahran, Jonas N. Kapp, Salla Valtonen, Allison Champagne, Jinying Ning, William Gillette, Andrew G. Stephen, Feng Hao, Andreas Plückthun, Harri Härmä, Tatu Pantsar, Kari Kopra

Version 1 posted 08 May 2024

534

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2

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