Search

4 results in Authors: Stefan Pöhlmann

Biological and Medicinal Chemistry

Probing Multivalent Lectin-Carbohydrate Binding via Multifunctional Glycan-Gold Nanoparticles: Implications for Blocking Virus Infection

Darshita Budhadev, Emma Poole, Inga Nehlmeier, Yuanyuan Liu, James Hooper, Elizabeth Kalverda, Uchangi Satyaprasad Akshath, Nicole Hondow, W. Bruce Turnbull, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 29 June 2020

455

Downloads

Polyvalent Glycomimetic-Gold Nanoparticle Conjugates reveal effects of glycan display on Multivalent Lectin-Glycan Interactions

Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier, Amy Kempf, Iain Manfield, Bruce Turnbull, Stefan Pöhlmann, Anna Bernardi, Xin Li, Yuan Guo, Dejian Zhou

Version 1 posted 03 January 2024

123

Downloads

A Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo

Version 1 posted 01 November 2022

187

Downloads

Probing Scaffold Size Effects on Multivalent Lectin-Glycan Binding Affinity, Thermodynamics and Antiviral Potency Using Polyvalent Glycan-Gold Nanoparticles

Rahman Basaran, Darshita Budhadev, Amy Kempf, Inga Nehlmeier, Nicole Hondow, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 22 January 2024

128

Downloads