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Biological and Medicinal Chemistry

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Reena Zutshi

5 results in Authors: Reena Zutshi

Biological and Medicinal Chemistry

Characterization of 2,4-dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9 and PfPKB

Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher Mansfield, Michael Chirgwin, Anna Truong, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 10 August 2023

144

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Biological and Medicinal Chemistry

A Chemical Probe Targeting AAK1 and BMP2K

Carrow Wells, Rafael Counago, Juanita C. Limas, Tuanny L. Almeida, Jeanette G. Cook, David Drewry, Jonathan Elkins, Opher Gileadi, Nirav Kapadia, Álvaro Lorente-Macías, Julie E. Pickett, Alexander J. Riemen, Roberta R. Ruela-de-Sousa, Timothy M. Willson, Cunyu Zhang, William J. Zuercher, Reena Zutshi, Alison D. Axtman

Version 1 posted 04 September 2019

646

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Biological and Medicinal Chemistry

Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity Against Blood Stage Parasites in vitro

Kareem Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy Havener, Michael Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed Helal, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 17 June 2022

196

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Biological and Medicinal Chemistry

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

Alfredo Picado, Apirat Chaikuad, Carrow Wells, Safal Shrestha, William Zuercher, Julie E. Pickett, Frank Kwarcinski, Parvathi Sinha, Chandi de Silva, Reena Zutshi, Shubin Liu, Natarajan Kannan, Stefan Knapp, David Drewry, Tim Willson

Version 1 posted 07 July 2020

827

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Biological and Medicinal Chemistry

Discovery of Potent Plasmodium falciparum Protein Kinase 6 (PfPK6) Inhibitors with a Type II Inhibitor Pharmacophore

Han Wee Ong, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy Havener, Michael Chirgwin, Kareem Galal, Caleb Willis, Andreas Krämer, Shubin Liu, Stefan Knapp, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 16 June 2022

431

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