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Biological and Medicinal Chemistry

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Organic Chemistry

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Rajiv Bedi

4 results in Authors: Rajiv Bedi

Biological and Medicinal Chemistry

Development of a novel class of CBP/EP300 bromodomain inhibitors which block TNF-α induced NFκB signaling

Katherine Gosselé, Irene Latino, Eleen Laul, Mariia Kirillova, Vlad Pascanu, Emanuele Carloni, Rajiv Bedi, Amedeo Caflisch, Santiago Gonzalez, Cristina Nevado

Version 1 posted 26 March 2024

426

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1

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Biological and Medicinal Chemistry

Structure-based design of a potent and selective YTHDC1 ligand

František Zálešák, Francesco Nai, Rajiv K. Bedi, Yaozong Li, Marcin Herok, Elena Bochenkova, Francesco Errani, Amedeo Caflisch

Version 1 posted 29 November 2023

494

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Biological and Medicinal Chemistry

Structure-based Design of CBP/EP300 Degraders: When Coopera-tivity Overcomes Affinity

Ivan Cheng-Sanchez, Katherine Gosselé, Leonardo Palaferri, Eleen Laul, Gionata Riccabella, Rajiv Bedi, Yaozong Li, Anna Müller, Amedeo Caflisch, Cristina Nevado

Version 1 posted 26 March 2024

377

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Biological and Medicinal Chemistry

Discovery of YTHDF2 ligands by fragment-based design

Annalisa Invernizzi, Francesco Nai, Rajiv Kumar Bedi, Pablo Andrés Vargas-Rosales, Yaozong Li, Elena Bochenkova, Marcin Herok, František Zálešák, Amedeo Caflisch

Version 1 posted 17 April 2025

103

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