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5 results in Authors: Michael O'Hagan

Biological and Medicinal Chemistry

Stiff-Stilbene Ligands Target G-Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

Michael O'Hagan, pablo Peñalver, Rosina S. L. Gibson, Juan Carlos Morales, M. Carmen Galan

Version 1 posted 23 December 2019

425

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Biological and Medicinal Chemistry

DNA G‑Quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease: dithienylethene ligands as effective antiparasitic agents

Manuel Pérez-Soto, Javier Ramos-Soriano, Pablo Peñalver, Efres Belmonte-Reche, Michael O'Hagan, Anne Cucchiarini, Jean-Louis Mergny, Carmen Galán, Manuel Carlos López-López, Carmen Thomas, Juan Carlos Morales

Version 1 posted 29 April 2024

108

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Biological and Medicinal Chemistry

Imide Condensation as a Strategy for the Synthesis of Core Diversified G-Quadruplex Ligands with Anti-Cancer and Anti-Parasitic Activity

Steven T. G. Street, pablo Peñalver, Michael O'Hagan, Gregory J. Hollingworth, Juan Carlos Morales, M. Carmen Galan

Version 2 posted 06 January 2021

606

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Organic Chemistry

Visible-Light Photoswitching of G-Quadruplex Ligand Binding Mode Allows Reversible Control of G-Tetrad Structure

Michael O'Hagan, Javier Ramos Soriano, Susanta Haldar, Juan Carlos Morales, Adrian Mulholland, M. Carmen Galan

Version 2 posted 14 February 2020

726

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Organic Chemistry

A bridged azobenzene derivative exhibits fully-reversible photocontrolled binding to a G-quadruplex DNA/duplex junction

Javier Ramos-Soriano, Y. Jennifer Jiang, Bowen Deng, Michael O'Hagan, Susanta Haldar, Aditya Grao, Sofia Oliveira, Adrian Mulholland, M. Carmen Galan

Version 1 posted 12 July 2024

125

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