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Biological and Medicinal Chemistry

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Matthias Kassack

3 results in Authors: Matthias Kassack

Biological and Medicinal Chemistry

Multicomponent Syntheses Enable the Discovery of Novel Quisinostat-Derived Chemotypes as Histone Deacetylase Inhibitors

Daniel Stopper, Susanna Buntrock, Kathrin Tan, Lais Pessanha de Carvalho, Linda Schäker-Hübner, Jana Held, Matthias Kassack, Finn Kristian Hansen

Version 2 posted 07 November 2024

125

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Biological and Medicinal Chemistry

Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties

Daniel Stopper, Lukas Biermann, Paris Watson, jingyu Li, Beate König, Matthew Gaynes, Lais Pessanha de Carvalho, Maria Hanl, Alexandra Hamacher, Linda Schäker-Hübner, Jana Held, David Christianson, Matthias Kassack, Finn Kristian Hansen

Version 1 posted 01 October 2024

264

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Biological and Medicinal Chemistry

Hydrazide-based class I HDAC inhibitors with HDAC3 preference completely reverse chemoresistance in a synergistic manner in platinum-resistant solid cancer cells

Fabian B. Kraft, Lukas Biermann, Linda Schäker-Hübner, Maria Hanl, Alexandra Hamacher, Matthias U. Kassack, Finn Kristian Hansen

Version 2 posted 02 August 2024

313

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