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Biological and Medicinal Chemistry

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Linda Schäker-Hübner

5 results in Authors: Linda Schäker-Hübner

Biological and Medicinal Chemistry

Groebke Blackburn Bienaymé-mediated multi-component synthesis of selective HDAC6 inhibitors with anti-inflammatory properties

Fabian Kraft, Jana Enns, Irina Honin, Jonas Engelhardt, Andrea Schöler, Shannon Smith, Jens Meiler, Linda Schäker-Hübner, Günther Weindl, Finn Kristian Hansen

Version 2 posted 19 December 2023

188

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Biological and Medicinal Chemistry

Development of the first non-hydroxamate selective HDAC6 degraders

Tim Keuler, Beate König, Nico Bückreiß, Fabian Kraft, Philipp König, Linda Schäker-Hübner, Christian Steinebach, Gerd Bendas, Michael Gütschow, Finn Kristian Hansen

Version 2 posted 24 August 2022

962

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Biological and Medicinal Chemistry

Difluoromethyl-1,3,4-oxadiazoles are selective, mechanism-based, and essentially irreversible inhibitors of histone deacetylase 6

Beate König, Paris R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker-Hübner, David W. Christianson, Finn Kristian Hansen

Version 4 posted 04 September 2023

869

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Biological and Medicinal Chemistry

Development and characterization of the first selective class IIb histone deacetylase degraders

Shiyang Zhai, Linda Schäker-Hübner, Maria Hanl, Lukas Jacobi, Dominika Ewa Pieńkowska, Jan Gerhartz, Rabea Voget, Michael Gütschow, Felix Meissner, Radosław P. Nowak, Christian Steinebach, Finn Kristian Hansen

Version 1 posted 16 July 2024

152

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Biological and Medicinal Chemistry

Hydrazide-based class I HDAC inhibitors with HDAC3 preference completely reverse chemoresistance in a synergistic manner in platinum-resistant solid cancer cells

Fabian B. Kraft, Lukas Biermann, Linda Schäker-Hübner, Maria Hanl, Alexandra Hamacher, Matthias U. Kassack, Finn Kristian Hansen

Version 1 posted 05 July 2024

133

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