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Biological and Medicinal Chemistry

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Kristin M. Riching

2 results in Authors: Kristin M. Riching

Biological and Medicinal Chemistry

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Satomi Imaide, Kristin M. Riching, Nikolai Makukhin, Vesna Vetma, Claire Whitworth, Scott J. Hughes, Nicole Trainor, Sarah D. Mahan, Nancy Murphy, Angus Cowan, Kwok-Ho Chan, Conner Craigon, Andrea Testa, Chiara Maniaci, Marjeta Urh, Danette L. Daniels, Alessio Ciulli

Version 2 posted 20 October 2021

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Biological and Medicinal Chemistry

Leveraging dual-ligase recruitment to enhance degradation via a heterotrivalent PROTAC

Adam G. Bond, Miquel Muñoz i Ordoño, Celia M. Bisbach, Conner Craigon, Nikolai Makukhin, Elizabeth A. Caine, Manjula Nagala, Marjeta Urh, Georg E. Winter, Kristin M. Riching, Alessio Ciulli

Version 1 posted 21 August 2024

2,422

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