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Biological and Medicinal Chemistry

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Karoline Scholzen

4 results in Authors: Karoline Scholzen

Biological and Medicinal Chemistry

Cyclic 5-Membered Disulfides Are Not Selective Substrates of Thioredoxin Reductase, but Are Opened Nonspecifically

Jan Felber, Lena Poczka, Karoline Scholzen, Lukas Zeisel, Martin S. Maier, Sander Busker, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias Arnér, Julia Ahlfeld, Oliver Thorn-Seshold

Version 2 posted 17 January 2022

908

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Biological and Medicinal Chemistry

Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif

Jan Felber, Lukas Zeisel, Lena Poczka, Karoline Scholzen, Sander Busker, Martin S. Maier, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 1 posted 24 March 2021

505

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Biological and Medicinal Chemistry

Piperazine-fused cyclic disulfides: high-performance bioreduction-activated cores for bifunctional probes and reagents

Lukas Zeisel, Jan G. Felber, Karoline C. Scholzen, Carina Schmitt, Alexander J. Wiegand, Leonid Komissarov, Elias S. J. Arnér, Oliver Thorn-Seshold

Version 2 posted 10 October 2023

856

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Biological and Medicinal Chemistry

Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe

Lukas Zeisel, Jan G. Felber, Lena Poczka, Karoline Scholzen, Dorian Cheff, Martin S. Maier, Qing Cheng, Min Shen, Matt D. Hall, Elias S. J. Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 2 posted 01 March 2022

1,101

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