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7 results in Authors: Julia Thorn-Seshold

Isoquinoline-Based Biaryls as a Robust Scaffold for Microtubule Inhibitors

Yvonne Kraus, Carina Glas, Benedikt Melzer, Li Gao, Constanze Heise, Monique Preusse, Julia Ahlfeld, Franz Bracher, Oliver Thorn-Seshold

Version 1 posted 06 August 2019

503

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Biological and Medicinal Chemistry

Working Paper

Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe

Lukas Zeisel, Jan G. Felber, Lena Poczka, Karoline Scholzen, Dorian Cheff, Martin S. Maier, Qing Cheng, Min Shen, Matt D. Hall, Elias S. J. Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 2 posted 01 March 2022

1,101

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Biological and Medicinal Chemistry

Working Paper

Self-reporting styrylthiazolium photopharmaceuticals: mitochondrial localisation as well as SAR drive biological activity

Li Gao, Yvonne Kraus, Andrea Stegner, Thomas Wein, Constanze Heise, Leonie von Brunn, Elena Fajardo-Ruiz, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 1 posted 21 February 2022

277

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Biological and Medicinal Chemistry

Working Paper

Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif

Jan Felber, Lukas Zeisel, Lena Poczka, Karoline Scholzen, Sander Busker, Martin S. Maier, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 1 posted 24 March 2021

504

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Biological and Medicinal Chemistry

Working Paper

Potent Hemithioindigo-Based Antimitotics Photocontrol the Microtubule Cytoskeleton in Cellulo

Alexander Sailer, Franziska Ermer, Yvonne Kraus, Rebekkah Bingham, Ferdinand H. Lutter, Julia Ahlfeld, Oliver Thorn-Seshold

Version 1 posted 31 July 2019

526

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Biological and Medicinal Chemistry

Working Paper

Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision

Alexander Sailer, Joyce Meiring, Constanze Heise, Linda Pettersson, Anna Akhmanova, Julia Thorn-Seshold, Oliver Thorn-Seshold

Version 1 posted 01 March 2021

494

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Citations

Biological and Medicinal Chemistry

Working Paper

Cyclic 5-Membered Disulfides Are Not Selective Substrates of Thioredoxin Reductase, but Are Opened Nonspecifically

Jan Felber, Lena Poczka, Karoline Scholzen, Lukas Zeisel, Martin S. Maier, Sander Busker, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias Arnér, Julia Ahlfeld, Oliver Thorn-Seshold

Version 2 posted 17 January 2022

907

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7 results in Julia Thorn-Seshold in Authors: Julia Thorn-Seshold

Isoquinoline-Based Biaryls as a Robust Scaffold for Microtubule Inhibitors

Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe

Self-reporting styrylthiazolium photopharmaceuticals: mitochondrial localisation as well as SAR drive biological activity

Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif

Potent Hemithioindigo-Based Antimitotics Photocontrol the Microtubule Cytoskeleton in Cellulo

Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision

Cyclic 5-Membered Disulfides Are Not Selective Substrates of Thioredoxin Reductase, but Are Opened Nonspecifically

7 results in Authors: Julia Thorn-Seshold