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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9

Whitney L. Petrilli, Gregory Adam, Roman S. Erdmann, Pravien Abeywickrema, Viju Agnani, Xi Ai, Jen Baysarowich, Noel Byrne, John Caldwell, Wonsuk Chang, Edward DiNunzio, Zhe Feng, Rachel Ford, Sookhee Ha, Yongcheng Huang, Brian Hubbard, Jennifer M. Johnston, Michael Kavana, Jean-Marie Lisnock, Rui Liang, Jun Lu, Zhijian Lu, Juncai Meng, Peter Orth, Oksana Palyha, Gopal Parthasarathy, Scott P. Salowe, Sujata Sharma, Jennifer Shipman, Stephen Soisson, Alison Strack, Hyewon Youm, Kake Zhao, Debbie Zinc, Hratch Zokian, George Addona, Karen Akinsanya, James R. Tata, Yusheng Xiong, Jason E. Imbriglio

Version 1 posted 09 July 2019

1,084

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Analytical Chemistry

Working Paper

Automated detection of controlled substances from sealed e-cigarettes.

Matthew Gardner, Celeste Bowden, Shoaib Manzoor, Gyles Cozier, Rachael Andrews, Sam Craft, Martine Skumlien, Peter Sunderland, Tom Tooth, Peter Collins, Alexander Power, Tom Haines, Tom Freeman, Jennifer Scott, Oliver Sutcliffe, Richard Bowman, Stephen Husbands, Christopher Pudney

Version 1 posted 12 August 2024

199

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Materials Science

Working Paper

Selective dissolution and re-precipitation by pH cycling enables recovery of manganese from surface nodules

Pravalika Butreddy, Sebastian Mergelsberg, Jennifer N Jocz, Dongsheng Li, Venkateshkumar Prabhakaran, Andrew J Ritchhart, Chinmayee V Subban, Jon Kellar, Scott R Beeler, Sarah W Keenan, Elias Nakouzi

Version 2 posted 24 September 2024

106

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Analytical Chemistry

Working Paper

A field-portable technology for illicit drug discrimination via deep learning of hybridized reflectance/fluorescence spectro-scopic fingerprints

Alexander Power, Matthew Gardner, Rachael Andrews, Gyles Cozier, Ranjeet Kumar, Tom Freeman, Ian Blagbrough, Jennifer Scott, Anca Frinculescu, Trevor Shine, Gillian Taylor, Caitlyn Norman, Herve Menard, Niamh Nic Daeid, Oliver Sutcliffe, Stephen Husbands, Richard Bowman, Tom Haines, Christopher Pudney

Version 2 posted 29 August 2024

280

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Organic Chemistry

Working Paper

Enabling Electrochemical C-O and C-N Arylation Libraries using Alternating Polarity in Flow

Jennifer Morvan, Koen P L Kuijpers, Dayne Fanfair, Bingqing Tang, Karolina Bartkowiak, Lars Van eynde, Evelien Renders, Scott Wolkenberg, Jesus Alcazar, Peter JJA Buijnsters, Mary-Ambre Carvalho, Alexander X Jones

Version 1 posted 19 June 2024

471

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Biological and Medicinal Chemistry

Working Paper

Rational exploration of 2,4-diaminopyrimidines as DHFR inhibitors active against Mycobacterium abscessus and Mycobacterium avium, two emerging human pathogens

Matheus Meirelles, Vitor Almeida, Jaryd Sullivan, Ian de Toledo, Caio dos Reis, Micael Cunha, Rachael Zigweid, Abraham Shim, Banumathi Sankaran, Elijah Woodward, Steve Seibold, Lijun Liu, Mohammad Mian, Kevin Battaile, Jennifer Riley, Christina Duncan, Frederick Simeons, Liam Ferguson, Kevin Read, Scott Lovell, Bart Staker, Marcel Behr, Ronaldo Pilli, Rafael Couñago

Version 1 posted 15 July 2024

101

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Catalysis

Working Paper

Photochemically-Mediated Nickel-Catalyzed Synthesis of N-(Hetero)aryl Sulfamides

R. Thomas Simons, Georgia Scott, Anastasia Gant Kanegusuku, Jennifer Roizen

Version 2 posted 21 January 2020

1,117

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1

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Materials Science

Working Paper

Amphiphilic salts as single-component, solvent-free, lithium electrolytes

Jiacheng Liu, Marvin Diaz-Segura, A. Scott Manning, Lingyu Yang, Sunil Upadhyay, Jonathan Whitmer, Jennifer Schaefer

Version 2 posted 02 April 2024

547

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8 results in Jennifer Scott in Authors: Jennifer Scott

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9

Automated detection of controlled substances from sealed e-cigarettes.

Selective dissolution and re-precipitation by pH cycling enables recovery of manganese from surface nodules

A field-portable technology for illicit drug discrimination via deep learning of hybridized reflectance/fluorescence spectro-scopic fingerprints

Enabling Electrochemical C-O and C-N Arylation Libraries using Alternating Polarity in Flow

Rational exploration of 2,4-diaminopyrimidines as DHFR inhibitors active against Mycobacterium abscessus and Mycobacterium avium, two emerging human pathogens

Photochemically-Mediated Nickel-Catalyzed Synthesis of N-(Hetero)aryl Sulfamides

Amphiphilic salts as single-component, solvent-free, lithium electrolytes

8 results in Authors: Jennifer Scott