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Biological and Medicinal Chemistry

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Last 3 years

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Irene Schaperdoth

2 results in Authors: Irene Schaperdoth

Biological and Medicinal Chemistry

Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase

Eliott Wenger, Ryan Martinie, Richiro Ushimaru, Christopher Pollock, Debangsu Sil, Aaron Li, Nhi Hoang, Gavin Palowitch, Brandt Graham, Irene Schaperdoth, Evan Burke, Ailiena Maggiolo, Wei-Chen Chang, Benjamin Allen, Carsten Krebs, Alexey Silakov, Amie Boal, J. Martin Bollinger Jr.

Version 4 posted 29 March 2024

1,194

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Biological and Medicinal Chemistry

An Unusual Ferryl Intermediate and its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO

Juan Pan, Eliott Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert Grossman, Carsten Krebs, J. Martin Bollinger Jr.

Version 1 posted 28 March 2024

414

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