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Biological and Medicinal Chemistry

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Han Wee Ong

3 results in Authors: Han Wee Ong

Biological and Medicinal Chemistry

Characterization of 2,4-dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9 and PfPKB

Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher Mansfield, Michael Chirgwin, Anna Truong, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 10 August 2023

130

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Biological and Medicinal Chemistry

Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity Against Blood Stage Parasites in vitro

Kareem Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy Havener, Michael Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed Helal, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 17 June 2022

168

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Biological and Medicinal Chemistry

Discovery of Potent Plasmodium falciparum Protein Kinase 6 (PfPK6) Inhibitors with a Type II Inhibitor Pharmacophore

Han Wee Ong, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy Havener, Michael Chirgwin, Kareem Galal, Caleb Willis, Andreas Krämer, Shubin Liu, Stefan Knapp, Emily Derbyshire, Reena Zutshi, David Drewry

Version 1 posted 16 June 2022

378

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