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Biological and Medicinal Chemistry

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Florian Friedrich

4 results in Authors: Florian Friedrich

Biological and Medicinal Chemistry

Efficient Crystallization of Apo Sirt2 for Small Molecule Soaking and Structural Analysis of Ligand Interactions

Florian Friedrich, Matthias Schiedel, Sören Swyter, Lin Zhang, Wolfgang Sippl, Mike Schutkowski, Oliver Einsle, Manfred Jung

Version 2 posted 26 November 2024

284

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Identification and Characterisation of Pyrimidine Nucleoside 2'-Hydroxylase

Ferdinand Genz, Florian Friedrich, Christoph Lönarz, Oliver Einsle, Manfred Jung, Michael Müller, Nico D. Fessner

Version 1 posted 15 November 2024

227

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Biological and Medicinal Chemistry

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation

Laura Sinatra, Anja Vogelmann, Florian Friedrich, Margarita Tararina, Emilia Neuwirt, Arianna Colcerasa, Philipp König, Lara Toy, Talha Yesiloglu, Sebastian Hilscher, Lena Gaitzsch, Niklas Papenkordt, Shiyang Zhai, Lin Zhang, Christophe Romier, Oliver Einsle, Wolfgang Sippl, Mike Schutkowski, Olaf Groß, Gerd Bendas, David Christianson, Finn Hansen, Manfred Jung, Matthias Schiedel

Version 3 posted 03 October 2023

587

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Biological and Medicinal Chemistry

Structure-activity studies of 1,2,4-oxadiazoles for the inhibition of the NAD+ dependent lysine deacylase Sirtuin2

Arianna Colcerasa, Florian Friedrich, Jelena Melesina, Patrick Moser, Anja Vogelmann, Pavlos Tzortzoglou, Emilia Neuwirt, Manuela Sum, Lin Zhang, Elizabeth Ramos-Morales, Christophe Romier, Oliver Einsle, Eric Metzger, Roland Schüle, Olaf Gross, Wolfgang Sippl, Manfred Jung

Version 2 posted 29 November 2023

393

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