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Biological and Medicinal Chemistry

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Finn K. Hansen

3 results in Authors: Finn K. Hansen

Biological and Medicinal Chemistry

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Christian Steinebach, Izidor Sosič, Aleša Bricelj, Arunima Murgai, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Annika Schmidt, Patricia Lemnitzer, Finn K. Hansen, Michael Gütschow, Jan Krönke, Marcus D. Hartmann

Version 1 posted 21 April 2023

1,399

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1

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Biological and Medicinal Chemistry

Development of a First-in-Class Small Molecule Inhibitor of the C-terminal Hsp90 Dimerization

Sanil Bhatia, Lukas Spanier, David Bickel, Niklas Dienstbier, Vitalij Woloschin, Melina Vogt, Henrik Pols, Beate Lungerich, Jens Reiners, Narges Aghaallaei, Daniela Diedrich, Benedikt Frieg, Julian Schliehe-Diecks, Bertan Boop, Franziska Lang, Mohanraj Gopalswamy, Jennifer Loschwitz, Baubak Bajohgli, Julia Skokowa, Arndt Borkhardt, Julia Hauer, Finn K. Hansen, Sander H.J. Smits, Joachim Jose, Holger Gohlke, Thomas Kurz

Version 1 posted 17 December 2021

510

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Biological and Medicinal Chemistry

Solid-phase synthesis of cereblon-recruiting selective histone deacetylase 6 degraders (HDAC6 PROTACs) with anti-leukemic activity

Laura Sinatra, Jing Yang, Julian Schliehe-Diecks, Niklas Dienstbier, Melina Vogt, Philip Gebing, Luisa M. Bachmann, Melf Sönnichsen, Thomas Lenz, Kai Stühler, Andrea Schöler, Arndt Borkhardt, Sanil Bhatia, Finn K. Hansen

Version 4 posted 11 November 2022

1,173

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