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5 results in Authors: Ewen Calder

Biological and Medicinal Chemistry

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Anna Skwarska, Ewen Calder, Deborah Sneddon, Hannah Bolland, Maria Odyniec, Ishna N. Mistry, Jennifer Martin, Lisa Folkes, Ester M. Hammond, Stuart Conway

Version 2 posted 23 March 2021

1,268

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Biological and Medicinal Chemistry

Discovering Covalent Cyclic Peptide Inhibitors of Peptidyl Arginine Deiminase 4 (PADI4) Using mRNA-Display with a Genetically Encoded Electrophilic Warhead

Isabel Mathiesen, Ewen Calder, Simone Kunzelmann, Louise Walport

Version 1 posted 16 August 2024

771

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Biological and Medicinal Chemistry

Hypoxia-Activated Pro-Drugs of the KDAC Inhibitor Vorinostat (SAHA)

Ewen D. D. Calder, Anna Skwarska, Ishna N. Mistry, Deborah Sneddon, Stuart Conway, Ester M. Hammond

Version 1 posted 16 October 2019

731

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1

Citations

Biological and Medicinal Chemistry

Fluorescent Amino Acid Initiated De Novo Cyclic Peptides for the Label-Free Assessment of Cell Permeability

Yuteng Wu, Teresa Bertran Domingo, James Rowley, Ewen D. D. Calder, Dhira Joshi, Louise Walport

Version 1 posted 06 May 2021

433

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Biological and Medicinal Chemistry

Indolequinone-based hypoxia-activated PROTACs (HAP-TACs) selectively degrade BRD4 in hypoxic cancer cells

Marta Serafini, Sophie Twigger, George Delfas, Maxim Mallerman, Elliot Bailey, Ewen Calder, Ester Hammond, Stuart Conway

Version 1 posted 21 June 2025

21

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