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Biological and Medicinal Chemistry

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Theoretical and Computational Chemistry

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Eric Therrien

3 results in Authors: Eric Therrien

Biological and Medicinal Chemistry

A Computational Physics-based Approach to Predict Unbound Brain-to-Plasma Partition Coefficient, Kp,uu

Morgan Lawrenz, Mats Svensson, Mitsunori Kato, Karen Dingley, Jackson Chief Elk, Zhe Nie, Yefen Zou, Zachary Kaplan, H. Rachel Lagiakos, Hideyuki Igawa, Eric Therrien

Version 1 posted 13 January 2023

1,616

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Biological and Medicinal Chemistry

In Silico Enabled Discovery of KAI-11101, a Preclinical DLK Inhibitor for the Treatment of Neurodegenerative Disease and Neuronal Injury

H. Rachel Lagiakos, Yefen Zou, Hideyuki Igawa, Eric Therrien, Morgan Lawrenz, Mitsunori Kato, Mats Svennson, Felicia Gray, Kristian K. Jensen, Markus K. Dahlgren, Robert D. Pelletier, Karen H. Dingley, Jeffrey A. Bell, Yuansong Jiang, Hua Zhou, Robert J. Skene, Zhe Nie

Version 1 posted 11 June 2024

580

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Biological and Medicinal Chemistry

Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform

Hideyuki Igawa, Zef A. Konst, Eric Therrien, Mee Shelley, Heidi Koldsø, Pieter H. Bos, Ana Negri, Andreas Verras, Jiaye Guo, Markus Dahlgren, Adam Levinson, Brendan T. Parr, Suresh E. Kurhade, Prashant Latthe, Rajesha Shetty, Sridhar Santhanakrishnan, Katherine Amberg-Johnson, Alan Futran, Christian Atsriku, Robert Pelletier, Zhijian Liu, Jeffery A. Bell, Sathesh Bhat, Mats Svensson, Aleksey I. Gerasyuto

Version 2 posted 21 June 2024

91

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