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Biological and Medicinal Chemistry

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Eric Metzger

3 results in Authors: Eric Metzger

Biological and Medicinal Chemistry

Structure-activity studies of 1,2,4-oxadiazoles for the inhibition of the NAD+ dependent lysine deacylase Sirtuin2

Arianna Colcerasa, Florian Friedrich, Jelena Melesina, Patrick Moser, Anja Vogelmann, Pavlos Tzortzoglou, Emilia Neuwirt, Manuela Sum, Lin Zhang, Elizabeth Ramos-Morales, Christophe Romier, Oliver Einsle, Eric Metzger, Roland Schüle, Olaf Gross, Wolfgang Sippl, Manfred Jung

Version 2 posted 29 November 2023

434

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Biological and Medicinal Chemistry

Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration

Anja Vogelmann, Matthias Schiedel, Nathalie Wössner, Annika Merz, Daniel Herp, Sören Hammelmann, Arianna Colcerasa, Garrison Komaniecki, Jun Young Hong, Manuela Sum, Eric Metzger, Emilia Neuwirt, Lin Zhang, Oliver Einsle, Olaf Groß, Roland Schüle, Hening Lin, Wolfgang Sippl, Manfred Jung

Version 2 posted 24 February 2022

763

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Biological and Medicinal Chemistry

Soft drug-inhibitors for the epigenetic targets Lysine-Specific Demethylase 1 (LSD1) and Histone Deacetylases (HDACs)

Johannes Seitz, Marina Auth, Tony Prinz, Mirjam Hau, Pavlos Tzortzoglou, Johannes Schulz-Fincke, Karin Schmidtkunz, Dominica Willmann, Eric Metzger, Lutz Hein, Sebastian Preissl, Roland Schüle, Manfred Jung

Version 2 posted 20 October 2023

522

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