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5 results in Authors: Elisée Wiita

Biological and Medicinal Chemistry

Optimization of N-piperidinyl-benzimidazolone derivatives as potent and selective inhibitors of 8-Oxo Guanine DNA Glycosylase 1

Olov Wallner, Armando Cázares-Körner, Emma Rose Scaletti, Geoffrey Masuyer, Tove Bekkhus, Torkild Visnes, Kirill Mamonov, Florian Ortis, Thomas Lundbäck, Maria Volkova, Tobias Koolmeister, Elisée Wiita, Olga Loseva, Monica Pandey, Evert Homan, Carlos Benítez-Buelga, Jonathan Davies, Martin Scobie, Ulrika Warpman Berglund, Christina Kalderén, Pål Stenmark, Thomas Helleday, Maurice Michel

Version 1 posted 24 December 2021

550

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Biological and Medicinal Chemistry

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

Emily C. Hank, Nicholas D'Arcy-Evans, Emma Rose Scaletti, Carlos Benítez-Buelga, Olov Wallner, Florian Ortis, Kaixin Zhou, Liuzhen Meng, Patricia Calvo, Ingrid Almlöf, Elisée Wiita, Sara Kosenina, Andreas Krämer, Maeve Long, Ann-Sofie Jemth, Holly Dawson, Josephine Stewart, Adam Dickey, Mikhael E. Astorga, Marek Varga, Evert J Homan, Martin Scobie, Stefan Knapp, Miguel de Vega, Leandro Sastre, Pål Stenmark, Thomas Helleday, Maurice Michel

Version 4 posted 02 January 2025

928

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1

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Theoretical and Computational Chemistry

In Silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Maurice Michel, Evert J. Homan, Elisee Wiita, Kia Pedersen, Ingrid Almlöf, Anna-Lena Gustavsson, Thomas Lundbäck, Thomas Helleday, Ulrika Warpman Berglund

Version 1 posted 25 October 2019

582

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Biological and Medicinal Chemistry

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches of DNA Repair Enzyme OGG1

Marek Varga, Florian Ortis, Emily Hank, Kaixin Zhou, Emma Scaletti Hutchinson, Alicia del Prado, Elisée Wiita, Alice Eddershaw, Natalie Rudolfova, Ingrid Almlöf, Stella Karsten, Kirill Mamonov, Kirsty Bentley, Olov Wallner, Evert J Homan, Martin Scobie, Thomas Helleday, Pål Stenmark, Miguel de Vega, Allan J. B. Watson, Maurice Michel

Version 1 posted 02 June 2025

151

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Biological and Medicinal Chemistry

Organocatalytic switches of OGG1 control ultrafast abasic site incision through compound pKa

Mario Kehler, Kaixin Zhou, Aurino Kemas, Alicia del Prado, Emma Scaletti Hutchinson, Elinor Hesslefors Nairn, Marek Varga, Yvonne Plattner, Yi Zong, Oryn Purewal-Sidhu, James Haslam, Elisee Wiita, Heather Gildie, Karolina Singerova, Zuzanna Szaruga, Ingrid Almlöf, Femke Hormann, Kang-Cheng Liu, Olov Wallner, Florian Ortis, Evert Homan, Opher Gileadi, Sean Rudd, Pål Stenmark, Miguel de Vega, Thomas Helleday, Nicholas D'Arcy-Evans, Volker Lauschke, Maurice Michel

Version 1 posted 13 March 2025

167

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