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    • David E. Heppner

    5 results in Authors: David E. Heppner

    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    The origin of potency and mutant-selective inhibition by bivalent ATP-allosteric EGFR inhibitors

    , Authors: Florian Wittlinger, Surbhi P Chitnis, Calvin D Pham, Tahereh Damghani, Ilse K Schaeffner, Matthew Q Deng, Blessing C Ogboo, Alexander Rasch, Tyler S Beyett, Brian Buckley, Frederic Feru, Tatiana Shaurova, Cornelius Knappe, Michael J Eck, Pamela A Hershberger, David A Scott, Stefan A Laufer, David E Heppner
    Version 1 posted 26 September 2023
    333
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    1
    Citations
    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors

    , Authors: Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik M. Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan A. Laufer, David E. Heppner
    Version 2 posted 19 September 2023
    639
    Downloads
    1
    Citations