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Probing Multivalent Lectin-Carbohydrate Binding via Multifunctional Glycan-Gold Nanoparticles: Implications for Blocking Virus Infection

Darshita Budhadev, Emma Poole, Inga Nehlmeier, Yuanyuan Liu, James Hooper, Elizabeth Kalverda, Uchangi Satyaprasad Akshath, Nicole Hondow, W. Bruce Turnbull, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 29 June 2020

455

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Biological and Medicinal Chemistry

Working Paper

Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations

Martin A. Fascione, Richard J. Spears, Robin L. Brabham, Darshita Budhadev, Tessa Keenan, Sophie McKenna, Julia Walton, James. A. Brannigan, A. Marek Brzozowski, Anthony J. Wilkinson, Michael Plevin

Version 1 posted 09 February 2018

723

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Nanoscience

Working Paper

Probing the pH-dependency of DC-SIGN/R based multivalent lectin-glycan interactions using polyvalent glycan-gold nanoparticles

Rahman Basaran, Darshita Budhadev, Yuan Guo, Dejian Zhou

Version 1 posted 21 December 2023

89

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Materials Chemistry

Working Paper

Polyvalent Glycan-Quantum Rods as Multifunctional Mechanistic Probes for Multivalent Glycan-Lectin Recognitions

James Hooper, Darshita Budhadev, Dario Fernandez Ainaga Ainaga, Nicole Hondow, Dejian Zhou, Yuan Guo

Version 1 posted 21 November 2022

137

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Nanoscience

Working Paper

Polyvalent Glycomimetic-Gold Nanoparticle Conjugates reveal effects of glycan display on Multivalent Lectin-Glycan Interactions

Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier, Amy Kempf, Iain Manfield, Bruce Turnbull, Stefan Pöhlmann, Anna Bernardi, Xin Li, Yuan Guo, Dejian Zhou

Version 1 posted 03 January 2024

123

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Biological and Medicinal Chemistry

Working Paper

The retaining Pse5Ac7Ac pseudaminyltransferase KpsS1 defines a new glycosyltransferase family (GTXXX)

Abigail Walklett, Emily Flack, Harriet Chidwick, Natasha Hatton, Tessa Keenan, Darshita Budhadev, Julia Walton, Gavin Thomas, Martin Fascione

Version 1 posted 04 December 2023

133

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Nanoscience

Working Paper

Probing Thermodynamics, Kinetics and Structural Details of Multivalent Lectin-Glycan Interactions by Quantum Dot-FRET

James Hooper, Yuanyuan Liu, Darshita Budhadev, Dejian Zhou, Yuan Guo

Version 1 posted 31 March 2022

182

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Nanoscience

Working Paper

Probing Scaffold Size Effects on Multivalent Lectin-Glycan Binding Affinity, Thermodynamics and Antiviral Potency Using Polyvalent Glycan-Gold Nanoparticles

Rahman Basaran, Darshita Budhadev, Amy Kempf, Inga Nehlmeier, Nicole Hondow, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 22 January 2024

128

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Nanoscience

Working Paper

A Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo

Version 1 posted 01 November 2022

187

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9 results in Darshita Budhadev in Authors: Darshita Budhadev

Probing Multivalent Lectin-Carbohydrate Binding via Multifunctional Glycan-Gold Nanoparticles: Implications for Blocking Virus Infection

Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations

Probing the pH-dependency of DC-SIGN/R based multivalent lectin-glycan interactions using polyvalent glycan-gold nanoparticles

Polyvalent Glycan-Quantum Rods as Multifunctional Mechanistic Probes for Multivalent Glycan-Lectin Recognitions

Polyvalent Glycomimetic-Gold Nanoparticle Conjugates reveal effects of glycan display on Multivalent Lectin-Glycan Interactions

The retaining Pse5Ac7Ac pseudaminyltransferase KpsS1 defines a new glycosyltransferase family (GTXXX)

Probing Thermodynamics, Kinetics and Structural Details of Multivalent Lectin-Glycan Interactions by Quantum Dot-FRET

Probing Scaffold Size Effects on Multivalent Lectin-Glycan Binding Affinity, Thermodynamics and Antiviral Potency Using Polyvalent Glycan-Gold Nanoparticles

A Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

9 results in Authors: Darshita Budhadev