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Biological and Medicinal Chemistry

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Daniel A. Guthy

2 results in Authors: Daniel A. Guthy

Biological and Medicinal Chemistry

Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates

Alan Zhang, Katherine Seiss, Sebastian Palacio-Ramirez, Laurent Laborde, Daniel Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Thomas Zoller, Christina Hebach, William R. Tschantz, Alexei Karpov, Gregory J. Hollingworth, Joseph A. D’Alessio, Stephane Ferretti, Matthew T. Burger

Version 1 posted 30 November 2023

1,475

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Biological and Medicinal Chemistry

Reversible Small Molecule pan-Ras Inhibitors Display Tunable Affinity for the Active and Inactive forms of Ras.

Charles Parry, Francesca Pellicano, Alexander W. Schüttelkopf, Kim Beyer, Justin Bower, Amy Bryson, Kenneth S. Cameron, Nichole M. Cerutti, Jonathan P. Clark, Stuart Davidson, Keneth Davies, Martin J. Drysdale, Jeffrey Engelman, Anna Estevan-Barber, Andrea Gohlke, Daniel A. Guthy, Min Hong, Alana Hopkins, Luke Hutchinson, Jennifer Konczal, Michel Maira, Duncan McArthur, Heather McKinnon, Ridvan Nepravishta, Nils Ostermann, Camila Pasquali, Katie Pollock, Angelo Pugliese, Nicholas Rooney, Niko Schmiedeberg, Paul Shaw, Camilo Velez-Vega, Christopher West, Ryan West, Frederic Zecri, John B. Taylor

Version 1 posted 04 November 2024

393

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