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Carsten E. Seyfert

2 results in Authors: Carsten E. Seyfert

Biological and Medicinal Chemistry

Activity and cryo-EM structure guided biosynthetic pathway engineering yields non-natural Darobactin antibiotics with superior activity against Gram-negative pathogens

Carsten E. Seyfert, Christoph Porten, Biao Yuan, Selina Deckarm, Fabian Panter, Chantal D. Bader, Janetta Coetzee, Felix Deschner, Kamaleddin H. M. E. Tehrani, Paul G. Higgins, Harald Seifert, Thomas Marlovits, Jennifer Herrmann, Rolf Müller

Version 2 posted 26 September 2022

708

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Biological and Medicinal Chemistry

New Genetically Engineered Derivatives of Antibacterial Darobac-tins Underpin their Potential for Antibiotic Development

Carsten E. Seyfert, Alison V. Müller, Danica J. Walsh, Joy Birkelbach, Andreas M. Kany, Christoph Porten, Biao Yuan, Daniel Krug, Jennifer Herrmann, Thomas C. Marlovits, Anna K. H. Hirsch, Rolf Müller

Version 1 posted 11 September 2023

175

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