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Catalysis

Working Paper

Automated Flow Synthesis of Artificial Heme Enzymes for Enantioselective Biocatalysis

Giulio Fittolani, Dennis A. Kutateladze, Andrei Loas, Stephen L. Buchwald, Bradley L. Pentelute

Version 1 posted 13 June 2024

138

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Biological and Medicinal Chemistry

Working Paper

Linearizable Macrocyclic Peptide Libraries for Affinity Selection-Mass Spectrometry

Michael A. Lee, Joseph S. Brown, Charlotte E. Farquhar, Andrei Loas, Bradley L. Pentelute

Version 1 posted 05 February 2024

531

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Organic Chemistry

Working Paper

Equimolar Cross-Coupling Using Reactive Coiled Coils for Stable Covalent Protein Assemblies

Hironori Takeuchi, Elee Shimshoni, Satish Gandhesiri, Andrei Loas, Bradley L. Pentelute

Version 1 posted 12 June 2024

66

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Biological and Medicinal Chemistry

Working Paper

Rapid Production of Native and Mirror-Image Tumor Necrosis Factor-α through the Synergy of Automated Flow Peptide Synthesis and Native Chemical Ligation

Ahmet Yesilcimen, Alex J. Callahan, Tara L. Travaline, Satish Gandhesiri, Olena S. Tokareva, Andrei Loas, John H. McGee, Bradley L. Pentelute

Version 1 posted 02 February 2024

330

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Theoretical and Computational Chemistry

Working Paper

Unsupervised machine learning leads to an abiotic picomolar peptide ligand

Joseph S. Brown, Somesh Mohapatra, Michael A. Lee, Roman Misteli, Yitong Tseo, Nathalie M. Grob, Anthony J. Quartararo, Andrei Loas, Rafael Gomez-Bombarelli, Bradley L. Pentelute

Version 1 posted 24 May 2023

945

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Organic Chemistry

Working Paper

Synthesis of Proteins by Automated Flow Chemistry

Nina Hartrampf, Azin Saebi, Mackenzie Poskus, Zachary P. Gates, Alexander J. Callahan, Amanda E. Cowfer, Stephanie Hanna, Sarah Antilla, Carly K. Schissel, Anthony J. Quartararo, Xiyun Ye, Alexander J. Mijalis, Mark D. Simon, Andrei Loas, Shunying Liu, Carsten Jessen, Thomas E. Nielsen, Bradley L. Pentelute

Version 1 posted 11 February 2020

2,748

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Biological and Medicinal Chemistry

Working Paper

Electrophile Scanning Reveals Reactivity Hotspots for the Design of Covalent Peptide Binders

Nathalie M. Grob, Clint Remarcik, Simon L. Rössler, Jeffrey Y. K. Wong, John C. K. Wang, Jason Tao, Corey L. Smith, Andrei Loas, Stephen L. Buchwald, Dan L. Eaton, Magdalena Preciado López, Bradley L. Pentelute

Version 1 posted 19 June 2023

1,119

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Regularized indirect learning improves phage display ligand discovery

Joseph S. Brown, Yitong Tseo, Michael A. Lee, Jeffrey Y.-K. Wong, Soojung Yang, Yehlin Cho, Chae Rin Kim, Andrei Loas, Ratmir Derda, Rafael Gomez-Bombarelli, Bradley L. Pentelute

Version 1 posted 28 July 2023

619

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Organic Chemistry

Working Paper

Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display

Alex J. Callahan, Satish Gandhesiri, Tara L. Travaline, Lia Lozano Salazar, Stephanie Hanna, Yen-Chun Lee, Kunhua Li, Olena S. Tokareva, Jean-Marie Swiecicki, Andrei Loas, Gregory L. Verdine, John H. McGee, Bradley L. Pentelute

Version 1 posted 03 February 2023

1,205

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10

Citations

Biological and Medicinal Chemistry

Working Paper

Abiotic peptides for the encoding of small molecule synthesis

Simon L. Rössler, Nathalie M. Grob, Stephen L. Buchwald, Bradley L. Pentelute

Version 1 posted 27 September 2022

1,540

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14 results in Bradley L. Pentelute in Authors: Bradley L. Pentelute

Automated Flow Synthesis of Artificial Heme Enzymes for Enantioselective Biocatalysis

Linearizable Macrocyclic Peptide Libraries for Affinity Selection-Mass Spectrometry

Equimolar Cross-Coupling Using Reactive Coiled Coils for Stable Covalent Protein Assemblies

Rapid Production of Native and Mirror-Image Tumor Necrosis Factor-α through the Synergy of Automated Flow Peptide Synthesis and Native Chemical Ligation

Unsupervised machine learning leads to an abiotic picomolar peptide ligand

Synthesis of Proteins by Automated Flow Chemistry

Electrophile Scanning Reveals Reactivity Hotspots for the Design of Covalent Peptide Binders

Regularized indirect learning improves phage display ligand discovery

Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display

Abiotic peptides for the encoding of small molecule synthesis

14 results in Authors: Bradley L. Pentelute