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Biological and Medicinal Chemistry

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Bradley Doak

4 results in Authors: Bradley Doak

Biological and Medicinal Chemistry

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain

Luke Adams, Lorna E. Wilkinson-White, Menachem J. Gunzburg, Stephen J. Headey, Martin J. Scanlon, Ben Capuano, Joel P. Mackay, Bradley Doak

Version 1 posted 25 March 2020

767

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Biological and Medicinal Chemistry

Selective binding of small molecules to Vibrio cholerae DsbA offers a starting point for the design of novel antibacterials

Geqing Wang, Biswaranjan Mohanty, Martin Williams, Bradley Doak, Rabeb Dhouib, Makrina Totsika, Róisín Macmahon, Gaurav Sharma, Dan Zheng, Matthew Bentley, Yanni Ka-Yan Chin, James Horne, David Chalmers, Begona Heras, Martin Scanlon

Version 1 posted 07 October 2021

204

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Biological and Medicinal Chemistry

Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates

Bradley Doak, Rebecca Whitehouse, Kieran Rimmer, Martin Williams, Begona Heras, Sofia Caria, Olga Ilyichova, Mansha Vazirani, Biswaranjan Mohanty, Jason Harper, Martin Scanlon, Jamie Simpson

Version 1 posted 17 February 2022

314

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1

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Biological and Medicinal Chemistry

NMR and SPR Fragment-Based Screening Can Produce Novel High Affinity Small Molecule Hits Against Structured RNAs

Brooke Kwai, Indu Chandrashekaran, Biswaranjan Mohanty, Menachem Gunzburg, Bradley Doak, Ashish Sethi, Shubhadra Pillay, David Lok, Sean Harrison, Pedro Serrano, Elisa Barile, Martin Scanlon

Version 1 posted 16 October 2024

141

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