Search

Clean synthetic strategies to dopamine-based biologically active molecules from lignin: A green path to drug discovery

Anastasiia Afanasenko, Xianyuan Wu, Alessandra DeSanti, Walid Elgaher, Andreas M. Kany, Roya Shafiei, Marie-Sophie Schulze, Thomas Schulz, Jörg Haupenthal, Anna K. H. Hirsch, Katalin Barta

Version 1 posted 18 October 2022

597

Downloads

3

Citations

Biological and Medicinal Chemistry

Working Paper

Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium Tuberculosis IspE

Maria Braun-Cornejo, Camilla Ornago, Vidhisha Sonawane, Jörg Haupenthal, Andreas M. Kany, Eleonora Diamanti, Gwenaëlle Jézéquel, Norbert Reiling, Wulf Blankenfeldt, Peter Maas, Anna K. H. Hirsch

Version 1 posted 20 May 2024

84

Downloads

Biological and Medicinal Chemistry

Working Paper

Targeting Plasmodium falciparum IspD in the Methyl-D-Erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on target with low micromolar whole-cell activity

Daan Willocx, Lorenzo Bizzarri, Alaa Alhayek, Patricia Bravo, Boris Illarionov, Katharina Rox, Jonas Lohse, Markus Fischer, Andreas M. Kany, Hannes Hahne, Matthias Rottmann, Matthias Witschel, Mostafa M. Hamed, Eleonora Diamanti, Anna K. H. Hirsch

Version 1 posted 26 March 2024

121

Downloads

Biological and Medicinal Chemistry

Working Paper

Unlocking the Antiviral Arsenal: Multiparametric Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E

Christina Karhan, Svenja Mareike Sake, Antonia Patricia Gunesch, Christina Grethe, Benedikt Hellwinkel, Alexander Felix Kiefer, Uladzislau Hapko, Andreas Martin Kany, Thomas Pietschmann, Anna Katharina Herta Hirsch

Version 1 posted 13 February 2024

207

Downloads

Theoretical and Computational Chemistry

Working Paper

DockM8: An All-in-One Open-Source Platform for Consensus Virtual Screening in Drug Design

Antoine Lacour, Hamza Ibrahim, Andrea Volkamer, Anna K. H. Hirsch

Version 1 posted 23 July 2024

571

Downloads

Nanoscience

Working Paper

Few Layer 2D Pnictogens (P & Sb) Catalyze the Alkylation of Soft Nucleophiles with Esters

Vicent Lloret, Miguel Ángel Rivero-Crespo, José Alejandro Vidal-Moya, Stefan Wild, Antonio Doménech-Carbó, Bettina S.J. Heller, Sunghwan Shin, Hans-Peter Steinrück, Florian Maier, Frank Hauke, Maria Varela, Andreas Hirsch, Antonio Leyva–Pérez, Gonzalo Abellán

Version 1 posted 26 September 2018

747

Downloads

Materials Science

Working Paper

Molecular Embroidering of Graphene

Tao Wei, Malte Kohring, Heiko B. Weber, Frank Hauke, Andreas Hirsch

Version 1 posted 11 May 2020

452

Downloads

Biological and Medicinal Chemistry

Working Paper

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Jelena Konstantinovic, Andreas M. Kany, Alaa Alhayek, Ahmed S. Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf W. Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch

Version 1 posted 24 April 2023

362

Downloads

Organic Chemistry

Working Paper

Enhancing Glycan Stability via Site-Selective Fluorination: Modulating Substrate Orientation by Molecular Design.

Alexander Axer, Ravindra P. Jumde, Sebastian Adam, Andreas Faust, Michael Schäfers, Manfred Fobker, Jesko Koehnke, Anna K.H. Hirsch, Ryan Gilmour

Version 1 posted 15 July 2020

506

Downloads

Biological and Medicinal Chemistry

Working Paper

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

Di Zhu, Sandra Johannsen, Tiziana Masini, Céline Simonin, Jörg Haupenthal, Boris Illarionov, Anastasia Andreas, Mahendra Awale, Robin M. Gierse, Tridia van der Laan, Ramon van der Vlag, Rita Nasti, Mael Poizat, Eric Buhler, Norbert Reiling, Rolf Müller, Markus Fischer, Jean-Louis Reymond, Anna K. H. Hirsch

Version 2 posted 11 April 2022

364

Downloads

Refine Search

13 results in Andreas Hirsch in Authors: Andreas Hirsch

Clean synthetic strategies to dopamine-based biologically active molecules from lignin: A green path to drug discovery

Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium Tuberculosis IspE

Targeting Plasmodium falciparum IspD in the Methyl-D-Erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on target with low micromolar whole-cell activity

Unlocking the Antiviral Arsenal: Multiparametric Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E

DockM8: An All-in-One Open-Source Platform for Consensus Virtual Screening in Drug Design

Few Layer 2D Pnictogens (P & Sb) Catalyze the Alkylation of Soft Nucleophiles with Esters

Molecular Embroidering of Graphene

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Enhancing Glycan Stability via Site-Selective Fluorination: Modulating Substrate Orientation by Molecular Design.

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

13 results in Authors: Andreas Hirsch