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4 results in Authors: Amy Kempf

A Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo

Version 1 posted 01 November 2022

284

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Probing Scaffold Size Effects on Multivalent Lectin-Glycan Binding Affinity, Thermodynamics and Antiviral Potency Using Polyvalent Glycan-Gold Nanoparticles

Rahman Basaran, Darshita Budhadev, Amy Kempf, Inga Nehlmeier, Nicole Hondow, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 22 January 2024

238

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Polyvalent Glycomimetic-Gold Nanoparticle Conjugates reveal effects of glycan display on Multivalent Lectin-Glycan Interactions

Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier, Amy Kempf, Iain Manfield, Bruce Turnbull, Stefan Pöhlmann, Anna Bernardi, Xin Li, Yuan Guo, Dejian Zhou

Version 1 posted 03 January 2024

258

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Materials Chemistry

Polyvalent carboxyl mannose-coated gold nanoparticles for probing multivalent lectin-glycan interaction and blocking virus infection

Rahman Basaran, Darshita Budhadev, Elena Dimitriou, Hannah Wootton, Gavin Miller, Amy Kempf, Inga Nehlmeier, Stefan Pöhlmann, Yuan Guo, Dejian Zhou

Version 1 posted 04 June 2025

7

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